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TRT for Pilots: FAA Testosterone Therapy and Medical Certification

TRT for pilots can be compatible with an FAA medical. Topical testosterone alone may qualify for Aviation Medical Examiner (AME) issuance; other listed treatments need the CACI checklist, including a complete blood count (CBC) within 90 days and hematocrit at 54% or lower. Enclomiphene is not acceptable. Your full treatment plan, stability, side effects, and records change the answer.

Who this is for: Adult men who are U.S. civilian pilots, or training to become pilots, and are on testosterone or thinking about it for low testosterone. It covers first-, second-, and third-class medicals, with a short section on BasicMed.

Who should look elsewhere: For military flight duties, aviators follow their service's aviation medical rules, not this process. Pilots certified outside the U.S. follow their own aviation authority. FAA-employed air traffic controllers use the same Low T form, but they send it to their Regional Flight Surgeon. This guide does not cover testosterone care for women, adolescents, or gender-affirming treatment.

That's the short version. The long version is where pilots get tripped up. An add-on medicine, a lab drawn on the wrong date, or a doctor's note the FAA won't accept can change the outcome. We'll show you exactly where those traps are.

What changes the answer:

  • For the CACI path: hematocrit above 54%, a history of a venous blood clot (such as DVT or PE), needing phlebotomy (blood removal as treatment), or an unstable treatment plan means your AME must defer to the FAA.
  • For CACI, first and second class: bring the paperwork every year. Third class: bring it at every required exam.
  • hCG needs a 7-day ground trial when you first start it. Clomiphene needs 14 days, and your AME must confirm you have no vision changes.
  • You have to report testosterone on your FAA application. Intentional falsification can put your certificates at risk.

Jump to the free AME prep worksheet

Pilot TRT FAA paths, records and care comparisons table 1: Comparison
Your treatment Where you land in FAA guidance
Topical testosterone only (gel or cream) Your AME decides. This is the simplest path.
Injectable or oral testosterone, Testopel Same-day issue is possible if every CACI box is checked and you are otherwise qualified.
Non-testosterone medicines: hCG, clomiphene, anastrozole, tamoxifen Listed for CACI review; all criteria and other qualifications still apply.
Enclomiphene Not acceptable under current FAA guidance.
CACI criteria not met, required phlebotomy, or treatment outside a Low T issuance branch Deferral. Your file goes to the FAA.

Sources: FAA Low T disposition table and CACI worksheet, both updated April 29, 2026; FAA Low T Status Summary, updated August 26, 2026.

Educational information, not medical advice and not FAA clearance. Your AME and the FAA make certification decisions. If you have chest pain or sudden trouble breathing, get emergency care now. New leg swelling, pain, warmth, or redness needs prompt medical assessment. (CDC blood-clot guidance)

TRT Provider Guide is the independent decision resource for testosterone replacement therapy — helping U.S. adults understand how low testosterone is evaluated, compare online and local care models and providers, and choose the next step that fits their health needs, fertility plans, budget, state, and care preferences, with every material claim verified and dated.


How does the FAA handle TRT for pilots?

Answer: The FAA looks at two things: the condition being treated and the medicine treating it. For low testosterone, its current guidance gives three paths: topical testosterone alone may qualify for AME issuance, other listed treatments use a checklist called CACI, and treatments outside those issuance branches require FAA review. Enclomiphene is explicitly not acceptable.

Three decisions people mix up

Three separate questions get treated as one:

  1. Should you be on testosterone? That's your treating doctor's call. They diagnose and prescribe.
  2. Can you hold a medical certificate? That's your AME's call, using FAA rules. Sometimes the FAA itself decides.
  3. Can you fly today? That's on you as pilot in command or a required pilot flight crewmember. A valid certificate doesn't cover a day when a medicine or symptom makes you unfit.

A prescription answers the first question only. A clinic that says, for example, "pilots do fine on our program" is answering a question that isn't theirs to answer.

Pilot TRT FAA paths, records and care comparisons table 2: Three decisions people mix up
Who Their job What it does not mean
You Report your medicines and history accurately. Bring the right records. Don't fly when you're not fit. Filling out a checklist doesn't clear you to fly.
Your treating doctor Diagnose, prescribe, and monitor. Write the clinical note or sign the FAA Status Summary. A prescription is not a medical certificate.
Your AME Applies current FAA guidance. Issues your certificate or defers. Can't promise an outcome before seeing your records.
The FAA Reviews deferred cases. Sets the terms of any special issuance. A deferral isn't a denial. It also isn't a promise.

What "CACI" means in plain English

CACI stands for Conditions AMEs Can Issue. For conditions on the list, the FAA hands your AME a worksheet. If you meet every item and you're otherwise qualified, the AME can issue your certificate at the exam, with no wait for Oklahoma City. Low testosterone (the medical term is hypogonadism, meaning your body doesn't make enough testosterone) is on that list. (FAA CACI conditions)

Miss one box, and the AME has to defer.


Which testosterone treatments and alternatives are FAA-acceptable?

Answer: Under current FAA Low T guidance, topical testosterone alone has a separate AME-issuance path; injectable and oral testosterone, Testopel, and certain non-testosterone medicines can qualify through CACI if all criteria are met. Enclomiphene is explicitly not acceptable. If a treatment does not fit a Low T issuance branch, the table directs deferral; ask your AME how the exact product and full regimen are classified.

This is the table we wish existed when we started digging. We built it from three FAA documents and checked it on October 30, 2026.

The FAA TRT Path Map

Every CACI row also requires all worksheet criteria and other certification requirements to be met. These are certification paths, not treatment recommendations.

Testosterone products and forms

Pilot TRT FAA paths, records and care comparisons table 3: The FAA TRT Path Map
Medicine or form FAA path What the AME needs Extra rule Bottom line
Testosterone gel or cream only Topical-only path. The AME may issue if the condition is controlled, your meds are acceptable, and you have no symptoms that affect flying. The AME's judgment. The FAA doesn't list a required lab for this path, but bring recent labs anyway. — Simplest path.
Testosterone injections (including cypionate and enanthate; the prescribed route depends on the product) CACI Blood count within 90 days with hematocrit ≤54%, plus a current detailed note or the FAA Status Summary First/second class: yearly. Third class: each required exam. Same-day issue is possible.
Oral testosterone (FDA-approved capsules such as Jatenzo, Kyzatrex, Tlando) CACI Same as injections Oral products carry blood-pressure warnings in their labels. Your blood pressure still has to meet FAA standards. Same-day issue is possible.
Testopel pellets CACI. The FAA names Testopel specifically. Same as injections Don't assume every pellet product counts as "Testopel." Tell your AME the exact product. Same-day issue is possible.

Non-testosterone medicines listed in the Low T guidance

Pilot TRT FAA paths, records and care comparisons table 4: The FAA TRT Path Map
Medicine FAA path What the AME needs Extra rule Bottom line
hCG (human chorionic gonadotropin) CACI Same as injections 7-day initial ground trial Can qualify after the required trial if all other criteria are met.
Clomiphene citrate CACI Same as injections, plus the AME confirms no vision side effects 14-day initial ground trial Can qualify after the required trial and AME vision check if all other criteria are met.
Anastrozole CACI Same as injections — Listed for CACI review.
Tamoxifen CACI, added April 29, 2026 Same as injections — Added to the CACI list in April 2026.
Enclomiphene citrate Not acceptable — — Not compatible with this path.

Other treatment situations

Pilot TRT FAA paths, records and care comparisons table 5: The FAA TRT Path Map
Situation FAA path What the AME needs Extra rule Bottom line
Treatment that requires phlebotomy Deferral Full packet to the FAA — FAA review.
A treatment whose classification is unclear (for example, gonadorelin, a testosterone troche, a nasal product, or a non-Testopel pellet) Ask the AME to identify the applicable FAA guidance. Give your AME the exact product and full regimen before you start. We did not verify a product-specific FAA determination for these examples. Treatment outside an issuance branch requires FAA review.

Sources: FAA Low T disposition table and FAA Low T CACI worksheet (both updated April 29, 2026); FAA Low T Status Summary (updated August 26, 2026). The final row identifies questions for the AME, not an FAA ruling on any single product.

Keep this straight: hCG, clomiphene, anastrozole, tamoxifen, and enclomiphene are not testosterone. They're different medicines that some clinics add to a plan or use instead of testosterone. They appear in the FAA table because the FAA classifies the whole treatment plan. Their listing isn't a sign that they're right for you. See hCG with TRT and enclomiphene vs clomiphene for the clinical side.

FAA listing does not mean a medicine is FDA-approved for male low testosterone. Using clomiphene, anastrozole, or tamoxifen for that purpose is off-label: it is outside the drug's FDA-approved uses. The FDA-approved hCG product Pregnyl includes selected cases of male hypogonadism caused by a pituitary signaling problem among its uses. That is not a blanket approval for an hCG-and-testosterone fertility plan.

Enclomiphene: a trap that can catch a pilot

Enclomiphene is heavily marketed online, often as the "fertility-friendly" option. The FAA's worksheet is blunt: "Enclomiphene citrate is NOT acceptable." On its own, enclomiphene is also not an FDA-approved drug (OPSS, Department of Defense dietary-supplement program).

Its cousin, clomiphene, is on the FAA list. The names are close. The FAA treats them differently. If you're on enclomiphene now, don't stop or switch on your own. Talk to your prescriber and your AME promptly, before flying.

Gel, injection, or pill: does the FAA care which one?

Yes, and topical-only treatment gets the lightest paperwork. That doesn't make it the right treatment for you. The best form depends on your health, your household (gels and creams can rub off on partners and kids), your budget, and your doctor's judgment. (Gel prescribing information; compounded-cream exposure case report) See TRT treatment options for those trade-offs.

FDA-approved vs. compounded: does it matter to the FAA?

The FAA's Low T documents name medicines and treatment forms, including the brand Testopel. They don't say how the FAA treats compounded versions. Here's what is clear:

  • FDA-approved means the FDA reviewed that exact product for safety, effectiveness, and quality.
  • Compounded means a drug's ingredients were mixed or altered to meet a patient's needs. Compounded drugs are not FDA-approved, and they aren't the same thing as an approved generic.

Give your AME the exact name, form, strength, and pharmacy of everything you take. Don't let anyone describe a compounded product to you as FDA-approved. (FDA compounding guidance)

The right TRT provider is not the same for every person — it depends on whether low testosterone has been properly evaluated, your symptoms and health history, your fertility plans, your state, your insurance or cash-pay preference, your treatment-format preference, your budget, and whether online or in-person care is the better starting point. Some situations belong with primary care, urology, endocrinology, reproductive urology, or urgent or emergency care when the symptoms warrant it. Because a general answer cannot resolve those for you, sort out your aviation questions with your AME, then use TRT Provider Guide's Find My TRT Path tool to explore general online care options. Use the worksheet below for the questions to ask before you pay. The tool is educational. It doesn't diagnose low testosterone, decide whether treatment is right for you, or assess FAA certification or whether you're fit to fly.

How the FAA Low T guidance changed

Pilot TRT FAA paths, records and care comparisons table 6: How the FAA Low T guidance changed
FAA document date What changed Why it matters
September 25, 2024 The Low T CACI path and Status Summary were set up. Created an office-issuance path for qualifying pilots.
September 24, 2025 Cardiovascular-disease and prostate-cancer history were removed as exclusions in the Low T CACI worksheet and Status Summary. Those conditions still need their own clinical and FAA assessment.
April 29, 2026 Tamoxifen was added as an acceptable medicine. Checklists published before this date may omit it.
August 26, 2026 The Status Summary hematocrit question was changed to greater than 54%. Use the current form. Old printouts still circulate.

Source: FAA AME Guide archives and updates and each document's own "Updated" date.

One caution on that history question. If your case does go to the FAA, your doctor's note still has to say whether you've had heart disease, blood clots, or prostate cancer. Don't read the narrower CACI question as "the FAA doesn't care about my heart." It does.


What paperwork do you bring to your AME if you're on TRT?

Answer: For gel or cream only, your AME decides, but recent labs help. For treatments listed in the CACI branch, bring a complete blood count (CBC) from the last 90 days showing hematocrit at or below 54%. Also bring either the FAA's Low T Status Summary signed by your treating physician or a detailed clinical progress note from a visit in the last 90 days.

Your preflight checklist for the CACI path

  • ☐ CBC (complete blood count) drawn within 90 days of your AME exam
  • ☐ Hematocrit 54% or lower on that CBC. Hematocrit is the share of your blood made up of red blood cells. Testosterone can push it up.
  • ☐ One of these two:
    • The FAA Low T Hypogonadism Status Summary, current version (August 26, 2026), signed by your treating physician with every answer in the "NO" column, or
    • A current, detailed clinical progress note from a visit in the last 90 days
  • ☐ The note covers your current medicines, doses, and any side effects
  • ☐ Any hCG or clomiphene ground trial is finished
  • ☐ Everything matches what you entered on MedXPress (more on that below)

The FAA notes that the Status Summary isn't required, since full records are also accepted. But the FAA says the Status Summary will "significantly DECREASE FAA review time." It's one page. Ask for it.

The five questions on the Status Summary

Your doctor answers yes or no. A single "yes" means your AME must defer.

  1. Are you unstable on your current plan, are changes recommended, or are there concerning side effects?
  2. Do you need phlebotomy?
  3. Any history of a blood clot (DVT or PE)?
  4. Does a CBC from the last 90 days show hematocrit greater than 54%?
  5. Does your doctor have any clinical concerns about you?

The form also lists your medicines. You'll see anastrozole, clomiphene, hCG, oral or injectable testosterone, Testopel, tamoxifen, and a line for "Other."

Why "OK to fly" letters get rejected

The FAA spells this out. A letter that says "Mr. Smith is ok to fly" is not acceptable. Patient-portal notes or after-visit summaries that lack the required details aren't sufficient either. A real progress note must include all of these (FAA pilot guidance on clinical progress notes):

Pilot TRT FAA paths, records and care comparisons table 7: Why "OK to fly" letters get rejected
What the note must include Plain English
History of the condition How low T was found and confirmed
Current medicines, doses, side effects Exactly what you take, how much, and any problems
Clinical exam findings What the doctor saw and checked
Results of testing Your labs
Diagnosis What you have
Assessment and plan What's being done and why
Prognosis How things are expected to go. Standard notes may skip this one, so ask your doctor to add it.
Follow-up When you'll be seen next

The FAA also describes the note as coming from an actual clinical encounter, "usually in office." If your care is all video visits, ask your AME ahead of time whether your prescriber's note will work. The signed Status Summary is another way to supply the required clinical information. Ask your AME whether the evaluation and documentation meet the requirements.

Does it have to be a urologist or endocrinologist?

Not always. The CACI worksheet accepts a note from a "urologist, endocrinologist, or treating physician." The Status Summary's signature line reads "endocrinologist, urologist, or physician." If your prescriber is a nurse practitioner or physician assistant, ask your AME before your exam whether their signature will be accepted. Don't find out at the exam.

Time it right: the 90-day window

Timing is a box that's easy to miss. For CACI, your labs and your doctor visit both have to land within 90 days before your AME exam.

Worked example: Your exam is March 15, 2027. Day 90 before that is December 15, 2026. Get your CBC and your doctor visit on or after December 15. Leave a week or so before the exam so results and paperwork are in hand. That buffer is our advice, not an FAA rule.

Want this done for your dates? Our free Pilot TRT Records & Questions Worksheet has a spot for your exam date, your 90-day start date, and every record you need. Print it, fill it in, and bring it to both appointments.


Can you fly while starting or changing testosterone?

Answer: A prescription and a valid certificate don't settle whether you can fly after a treatment change. The FAA's MedGuide says most new medicines need a 48-hour wait before safety-related duties, with shorter or longer waits for some medicines; hCG and clomiphene have initial ground trials of 7 and 14 days. Side effects that could affect flight safety mean you don't fly; ask your AME what applies to your exact plan.

The FAA's general rule for new medicines

The FAA's archive records MedGuide version 1.0 as published September 30, 2026. Its guidance page was updated October 27, 2026. Its general rules (FAA MedGuide):

  • When you start a new medicine, in most cases, a 48-hour wait is required before returning to flying. Higher-risk medicines can need longer; some medicines with minimal body-wide effects may have a shorter wait.
  • The wait isn't only about the medicine. The FAA may want a longer stretch to confirm the condition itself is stable.
  • If a concerning side effect shows up, stop flying right away and contact your treating doctor and/or the FAA.

MedGuide is version 1.0. We could not retrieve and verify a testosterone-specific entry in the interactive table. Don't treat "48 hours" as TRT clearance. Ask your AME to confirm the wait for your exact medicine and condition.

Ground trials at a glance

Pilot TRT FAA paths, records and care comparisons table 8: Ground trials at a glance
If you start… Initial ground trial (FAA Low T worksheet) Example
hCG 7 days Start June 1 → seven full days end June 8 at the starting time; this is not flight clearance
Clomiphene 14 days, plus the AME confirms no vision changes Start June 1 → fourteen full days end June 15 at the starting time; this is not flight clearance
Testosterone (any form) No Low T-specific trial stated. Ask your AME to apply the current medication guidance to your exact product and condition. Ask before your first flight on treatment

"Initial" means the first time you start the medicine. It doesn't mean after every dose. If you stop and restart, or change the dose, ask your AME.

The rule that applies between exams

Federal rule 14 CFR 61.53 says you can't act as pilot in command or a required pilot flight crewmember when you know, or have reason to know, about a medical condition that makes you unable to meet your medical standard. That rule covers side effects from a new medicine too (eCFR, 14 CFR 61.53). Your certificate doesn't override it.

Our editorial take: Coordinate any treatment start or change with your prescriber and AME, including time off flying, clinical monitoring, and the records needed for your next exam. A recent medical exam does not waive those obligations.


Do you have to report TRT to the FAA?

Answer: Yes. Your FAA application asks about every medicine you currently take (Item 17a), your medical history (Item 18), and health-professional visits in the last three years (Item 19). Report TRT accurately; intentional falsification can put your certificates at risk.

Pilot TRT FAA paths, records and care comparisons table 9: Do you have to report TRT to the FAA?
Where on MedXPress What goes there
Item 17a: current medications Every prescription and nonprescription medicine, including your testosterone and any add-ons
Item 18: medical history The condition being treated, answered according to the item's instructions
Item 19: visits in the last 3 years Visits to a physician, physician assistant, nurse practitioner, and others listed. Multiple visits to the same health professional for the same condition can go on one line.

Sources: FAA application history items and Item 19 guidance.

"I'm just optimizing, not diagnosed." You still report it.

The claim is that if there's no formal diagnosis, there's nothing to report. Wrong. Item 17a asks about medications you use, period. And the FAA's CACI path is built for diagnosed, treated hypogonadism. Testosterone is a Schedule III controlled substance and requires a valid prescription. Do not take testosterone outside lawful medical care or hide its use from your AME. (DEA drug scheduling)

"Does the FAA drug test for testosterone?"

That's the wrong question. Whether a drug panel picks it up doesn't change what you must report. For the testing side, see the drug-testing section of our TRT steroids guide.

Already on TRT and didn't list it last time?

Don't guess, and don't wait for your exam to bring it up. Talk to your AME, an aviation medical consultant, or an aviation attorney before your next application. If you're an AOPA member with Pilot Protection Services, that's a natural first call. We can't give legal advice. We can tell you that hiding it is the wrong fix.


What causes an FAA deferral on TRT, and what happens next?

Answer: For CACI, your AME must defer if your hematocrit is above 54%, you need phlebotomy, you've had a venous blood clot, your treatment isn't stable, your doctor flags a concern, or another required criterion is not met. The Low T disposition table also directs deferral for required phlebotomy and treatment outside an issuance branch, with FAA review for possible special issuance. A deferral isn't a denial, and it does not make an expressly unacceptable medicine acceptable.

Pilot TRT FAA paths, records and care comparisons table 10: What causes an FAA deferral on TRT, and what happens next?
Deferral trigger Why it matters in a cockpit What to do before your exam
Hematocrit over 54% on the CACI path Increased red-cell mass can increase clot risk Tell your prescriber now. Dose or format changes are their call.
Needs phlebotomy The FAA treats this as its own deferral category Bring full records and expect FAA review
Venous blood clot (such as DVT or PE) history Outside the Low T CACI criteria; the history needs FAA assessment Expect FAA review
Unstable plan or recommended changes The FAA wants a settled regimen Discuss treatment changes and exam timing with your prescriber and AME
Side effects that affect flying Direct safety issue Don't fly. Call your doctor.
An unacceptable medicine or treatment outside an issuance branch Enclomiphene is expressly unacceptable; other unclear products need AME classification Ask your AME before you start, not after
Missing or late records The AME can't check the boxes Use the 90-day window and the worksheet below

High hematocrit: a TRT issue pilots need to address

Testosterone tells your body to make more red blood cells. Some is expected. Too much thickens the blood. The FAA's CACI worksheet cites the Endocrine Society's testosterone guideline alongside its 54% criterion.

Two points matter here. First, 54% is a certification line, not a target. Your doctor manages your levels. Second, don't plan on "just donating blood" to sneak under the line. The FAA lists treatment that requires phlebotomy as a deferral trigger. More on this in TRT and high hematocrit and TRT bloodwork frequency.

Special issuance and AASI in plain English

  • Special issuance: After a deferral, the FAA can grant an authorization to issue your certificate with conditions.
  • AASI (AME Assisted Special Issuance): Once you have that authorization, your AME can reissue at later exams if you bring what it requires.

The FAA's Low T AASI sheet lists several reasons to defer again. These include starting a new form of treatment, a new venous blood clot, hematocrit reaching 55 or higher, or new side effects apart from the mild skin irritation and acne allowed by the sheet (FAA Low T AASI). If you have an authorization, follow its terms and ask your AME which current pathway applies. The AASI sheet's separate 55% trigger does not change the CACI requirement of 54% or lower.

We won't quote you a processing time. It varies, and nobody can promise one. What we can say: a complete packet is the one thing you control.


Does first class, third class, or BasicMed change anything?

Answer: The Low T guidance covers every certificate class, with different CACI documentation intervals. First- and second-class pilots supply the CACI information once a year; third-class pilots supply it at each required exam. BasicMed has its own process with a state-licensed physician.

Pilot TRT FAA paths, records and care comparisons table 11: Does first class, third class, or BasicMed change anything?
Certificate or separate framework Low T records or process Who reviews
First class Annually Your AME, or the FAA if deferred
Second class Annually Your AME, or the FAA if deferred
Third class With each required exam Your AME, or the FAA if deferred
BasicMed Not part of the CACI process A state-licensed physician, using the FAA's Comprehensive Medical Examination Checklist
FAA air traffic controllers Same Status Summary Regional Flight Surgeon

Sources: FAA CACI worksheet (April 29, 2026), Status Summary (August 26, 2026), and BasicMed. This table is about records, not about how long your certificate lasts.

Airline and corporate pilots

Flying may be your livelihood, so paperwork delays can carry real costs. Our editorial view: a local urologist or endocrinologist can be a useful starting point when you need specialist evaluation, in-person care, or insurance billing. The FAA accepts documentation from those specialists or a treating physician; first-class status alone does not require a local specialist. Bring them our worksheet, because the required note has specific aviation details.

BasicMed pilots

Under BasicMed, a one-time special issuance is required only for certain mental health, neurological, and heart conditions (FAA BasicMed). Low testosterone isn't one of them. You still list your medicines on the BasicMed checklist, and 14 CFR 61.53 still applies on every flight. You must still meet all BasicMed eligibility and operating requirements.

Student pilots already on TRT

Your first medical sets the tone. The FAA says a CACI condition can be cleared on the first exam if every criterion is met. Show up with the full packet.


What health issues can change the TRT and FAA conversation?

Answer: Low testosterone has to be properly diagnosed, and other health issues can change both your treatment and your FAA review. Raise fertility plans, sleep apnea, blood pressure, past blood-count problems, and heart or prostate history with your doctor first. Meeting the Low T rules doesn't settle another condition's FAA requirements.

Confirm the diagnosis first

The Endocrine Society recommends diagnosing low testosterone only when you have matching symptoms or signs and testosterone that is clearly and consistently low, confirmed with a repeat early-morning, fasting test (Endocrine Society guideline). One low number isn't a diagnosis. Neither is a quiz.

Pilots have a wrinkle here: red-eyes and early report times scramble sleep, and poor sleep can lower testosterone. (Sleep-restriction research) Ask your doctor how to time your tests around your real schedule. More in our low-testosterone testing guide.

Fertility comes before the prescription

Testosterone from outside the body can lower sperm production. The Endocrine Society recommends against starting testosterone in men who plan to have children soon. If kids are in your plans, see a urologist or reproductive urologist before starting. Nobody can promise that fertility will be protected or return on a schedule. See TRT and fertility.

Blood pressure and sleep apnea

In February 2025 the FDA announced removal of boxed-warning language about increased adverse cardiovascular outcomes, based on the large TRAVERSE trial. It also required blood-pressure information and a new warning for products that did not already have one (FDA, February 28, 2025). Blood pressure is its own FAA exam item, so watch it.

Sleep apnea is also its own FAA issue with its own rules. Testosterone can worsen sleep apnea in some patients; the Endocrine Society recommends against starting it in men with untreated severe obstructive sleep apnea. See TRT and sleep apnea.

Thyroid medicine on top of TRT

Some programs bundle thyroid medicine with testosterone. If you have diagnosed hypothyroidism, the FAA has separate guidance, including CACI for qualifying primary hypothyroidism. If you don't, a thyroid medicine is still something you must report and your AME will ask about. Know why it's in your plan before you accept it. See TRT and hypothyroidism.

What the 2026 FDA label news means for pilots

On June 18, 2026, the FDA requested changes to testosterone labels. These would remove the statement that safety and effectiveness for age-related hypogonadism have not been established and revise prostate-cancer and enlarged-prostate safety information (HHS, June 18, 2026). Requested doesn't mean every label has changed. And none of it changes FAA rules. Your AME still goes by the FAA documents above.


The Pilot TRT Records and Questions Worksheet

Answer: This free worksheet puts the key FAA records and questions in one place, with dates. Take it to your treating doctor first, then to your AME. It is not an FAA form or an eligibility test; it's a preflight checklist for the paperwork.

My dates

  • AME exam date: ____________________
  • 90 days before my exam, if required for my path (labs and doctor visit on or after this date): ____________________
  • Certificate class (1st / 2nd / 3rd / BasicMed): ____________________
  • Treating doctor appointment: ____________________
  • Existing FAA letter or authorization to bring: ____________________
Pilot TRT FAA paths, records and care comparisons table 12: The Pilot TRT Records and Questions Worksheet
Record or question Ask Date done Still need
How was my low testosterone confirmed, and what's causing it? Treating doctor
Exact name, form, strength, dose, and pharmacy of every medicine, plus start or change dates Treating doctor
Is anything in my plan expressly unacceptable, such as enclomiphene, or in need of AME classification, such as gonadorelin? Treating doctor + AME
Which FAA path am I on: topical-only, CACI, or deferral? AME
CBC with hematocrit, drawn within 90 days of my exam if required for my path Treating doctor / lab
Signed FAA Low T Status Summary or a detailed progress note, including prognosis Treating physician
Notes on side effects, blood clots, phlebotomy, heart or prostate history Treating physician
Ground trial dates for hCG or clomiphene, if prescribed AME
What wait applies before I fly after starting or changing treatment? AME
What goes on MedXPress Items 17a, 18, and 19? AME
Will the clinic answer my AME's follow-up questions? How? Clinic
Fees for records, forms, extra visits, and extra labs Clinic + AME

Bring up before you start: fertility plans, your sleep schedule and any sleep apnea, blood pressure, past blood-count problems, and heart, clot, or prostate history.

Last question to ask at every visit: "What's my next step, who owns it, and what has to be done before my exam or my next flight?"

Don't use this worksheet to start, stop, or change any medicine. Treatment calls belong to your doctor. Certification calls belong to your AME and the FAA.


How do you choose a TRT provider as a pilot?

Answer: As a pilot, pick a prescriber who can coordinate medically appropriate care with your AME's documentation needs. That includes the exact medicine list, blood tests within the window your path requires, and a physician who will provide the FAA Status Summary or a full progress note. Local care can fit specialist or insurance needs; an online program is an option only if its treatment, state coverage, monitoring, and records meet your needs.

Nine questions to ask any clinic before you pay

  1. Is the person who prescribes for me a physician (MD or DO), or could it be a nurse practitioner or physician assistant?
  2. Will that physician sign the FAA Low T Status Summary, or write a detailed progress note that includes prognosis?
  3. Does your lab work include a CBC with hematocrit? Is it drawn from a vein or a finger-prick? How often?
  4. What is every medicine in the proposed plan, why is it needed, and can I review the exact products with my AME before treatment?
  5. Is the medicine FDA-approved or compounded, and which pharmacy dispenses it?
  6. Is there a minimum commitment, and what does canceling cost?
  7. How will you arrange appropriate repeat early-morning testosterone testing, and is the repeat test included?
  8. What will the first year cost with medication, shipping, labs, extra visits, records, and FAA forms included?
  9. Can the assigned clinician treat me in the state where I will actually be during each visit?

If a clinic cannot answer these questions, resolve the gaps before paying.

How the main care routes compare for pilots

TRT Provider Guide has paid affiliate relationships with Male Excel and Hone Health. The provider links on this page go to their public information pages. Commercial relationships do not change our editorial conclusions. See our affiliate disclosure.

Provider facts are what each company states on its own website, read October 30, 2026. We checked the documents, not patient outcomes or the willingness of an assigned physician to complete FAA forms. Prices change. Confirm before you pay.

Pilot TRT FAA paths, records and care comparisons table 13: How the main care routes compare for pilots
Care comparison Local urologist or endocrinologist Male Excel Hone Health
Fit to investigate Complex history, insurance users, people who want an in-person specialist or FDA-approved products Pilots whose clinician considers topical therapy appropriate and who accept cash-pay care, compounded cream, and the documentation questions below Pilots comparing physician visits and included monitoring; Premium explicitly lists full CBCs
Testosterone forms FDA-approved gels, injections, oral products; Testopel availability varies by practice Cypionate injections (daily, under the skin, as the provider describes) and compounded Lipoderm cream; confirm the exact injectable product Cypionate injections; compounded cream and troches. Confirm whether the exact injection is manufactured or compounded.
FAA path of main option Determined from the exact treatment and full record A testosterone-only topical plan may fit row A; injections may fit CACI. The AME must review the whole plan, including thyroid medicine. A testosterone-only topical plan may fit row A; injections may fit CACI. Troches need AME classification.
Enclomiphene restriction Depends on the doctor's proposed plan Public pages conflict: Triclozene's product page names enclomiphene; the pricing page names clomiphene. Do not assume the blend is FAA-acceptable. Enclomiphene is offered, and it's not FAA-acceptable
Add-ons to ask about Depend on your diagnosis Plans are sold "with Thyroid." Triclozene also contains thyroid ingredients; its clomiphene-versus-enclomiphene identity needs clarification. Optional add-ons; review each one with your clinician and AME
Labs A clinician can order a venous CBC; insurance coverage and cost vary At-home blood-spot panel: testosterone, estradiol, DHEA-S, Free T3, PSA. No CBC listed in that panel. The homepage also states blood testing every six months; the full follow-up panel was not confirmed. Plus: eight initial markers; hematocrit at TRT confirmation and specified later checks, not a listed full CBC. Premium: 50+ initial markers including a full CBC, with CBCs in scheduled follow-ups.
Who prescribes Physician "Licensed medical provider"; consent describes physicians and other professionals, so confirm the assigned clinician and FAA-signature arrangements Licensed physicians through Hone-affiliated practices, according to its plan documents
Published pricing Varies by insurance $99 consult (includes the at-home test and treatment plan), $99/month membership with unlimited e-visits, injections from $120/month, cream from $132/month, billed every two months Plus: $45 initial test, $45 at-lab or $80 at-home confirmation, $135/month. Premium: $65 initial test, $25 at-lab confirmation, $155/month. Medication extra: injections from $28 per vial; cream from $60/month.
Our first-year price model Depends on your plan Cream ≈ $2,871; injections ≈ $2,727, before shipping, tax, and any separate testing or FAA-related costs With at-lab confirmation: Plus $2,046 in the $28/month medication-cost example or $2,430 for starting-price cream; Premium $2,286 or $2,670. These are price illustrations, not personal quotes.
Commitment Varies "No Contract, Cancel Anytime"; existing charges and refill deadlines still matter Monthly; membership and pending medication orders need separate cancellation
Insurance Depends on your plan, diagnosis, practice, and product No; provider says HSA/FSA eligibility may apply Cash-pay service; provider says HSA/FSA accepted. A local pharmacy bills separately if you transfer the prescription.

Sources: Male Excel pricing, hormone test, homepage monitoring and state FAQ, and telehealth consent; Hone's current Plus and Premium plan documents and Plus and Premium lab schedules. These plan-specific pages give more precise terms than Hone's general cost article.

What do the first-year numbers include?

The figures below use 12 monthly membership payments and the published medication prices. They include the stated setup and confirmation fees for each example, but they are not a complete quote for your care.

Pilot TRT FAA paths, records and care comparisons table 14: What do the first-year numbers include?
Price scenario First-year calculation Published subtotal
Male Excel cream $99 + ($99 × 12) + ($132 × 12) $2,871
Male Excel injections $99 + ($99 × 12) + ($120 × 12) $2,727
Hone Plus, at-lab confirmation, $28/month medication-cost example $45 + $45 + ($135 × 12) + ($28 × 12) $2,046
Hone Plus, at-lab confirmation, starting-price cream $45 + $45 + ($135 × 12) + ($60 × 12) $2,430
Hone Premium, at-lab confirmation, $28/month medication-cost example $65 + $25 + ($155 × 12) + ($28 × 12) $2,286
Hone Premium, at-lab confirmation, starting-price cream $65 + $25 + ($155 × 12) + ($60 × 12) $2,670

For Plus, choosing the $80 home confirmation instead of the $45 lab option adds $35, making those examples $2,081 and $2,465. Hone now lists injections from $28 per vial; the $28/month example is a price illustration, not a prescribed dose or a promise that one month's medication will cost that amount. Your real cost depends on your dose. Hone's cost page also shows an injection-cost example of $112/month, which would bring Plus with at-lab confirmation to about $3,054, or Premium to $3,294.

Before you pay, add what the quote leaves out: Male Excel shipping and handling, any tax, extra diagnostic or repeat tests, a separately ordered CBC, FAA forms or record fees, your AME exam, and any specialist visits or additional medication not included. Hone says its standard shipping, scheduled follow-up labs, and consultations are included; a separate CBC or FAA form is not established as an included extra. A local pharmacy sets its own medication price. Ask for the first charge, refill charges, and a full 12-month quote in writing. Our TRT cost guide explains the broader cost categories.

Is the program available where you will be during visits?

Male Excel's hormone-treatment FAQ excludes Alabama, Alaska, Arkansas, Connecticut, Hawaii, Idaho, Louisiana, Minnesota, Mississippi, New Hampshire, and Rhode Island. It does not clearly establish District of Columbia coverage. Hone's men's TRT coverage depends on the plan: Plus lists 35 states and Premium 34. New York appears under Premium only; Hawaii and South Dakota appear under Plus only. (Male Excel state FAQ, Hone state list)

For a pilot who travels, your home address isn't the only question. Tell the clinic where you will physically be during each appointment and confirm that its clinician can lawfully treat you there. HHS explains that cross-state practice depends on state rules. A public coverage list is not a check of your assigned clinician's license. Ask for the clinician's name and license details before the visit.

What happens to refills, refunds, and records if flying is delayed?

Pilot TRT FAA paths, records and care comparisons table 15: What happens to refills, refunds, and records if flying is delayed?
Question Male Excel's published terms Hone's published terms
Refills The FAQ describes a 60-day refill process and a 48-hour response window after the reminder before billing and shipping. Refills are automatic under the prescribed schedule; medication charges may occur about a week before the prior supply ends.
Cancellation and refunds No contract; terms generally make sales and subscription charges nonrefundable unless a separate written policy applies. The 90-day guarantee has conditions and covers initial membership fees, not every treatment cost. Submit the membership cancellation form before renewal; no partial-month refund. Cancel pending prescriptions separately. Processed or shipped medication cannot be canceled or refunded; shipped test kits are nonrefundable.
Pharmacy choice The FAQ names Anazao Health Corp. and WellDyneRx-FL; terms require a contracted pharmacy. Confirm which pharmacy would dispense your exact prescription. The sourcing page describes a pharmacy network without naming your assigned pharmacy. Hone says you can ask to use a local pharmacy; membership continues and the pharmacy bills you separately.
Records and FAA forms Consent says you can request records, with preparation or delivery costs. A physician's willingness to complete the FAA form was not confirmed. Full clinical-note access, FAA-form completion, and any fees need confirmation with the clinical practice before payment; included consultations alone do not prove that service.

Sources: Male Excel FAQ, terms, guarantee terms, and consent; Hone cancellation policy, refill process, pharmacy sourcing, and local-pharmacy policy.

Ask for a copy of the complete CBC and clinical note, the fee, and the expected delivery date. Ask whether the clinic will answer your AME's follow-up questions and what keeps billing if certification is delayed. Canceling a subscription is a billing action; treatment changes still belong with your prescriber.

Male Excel for pilots: check the topical plan and paperwork

May fit: a pilot whose clinician finds topical treatment appropriate and who wants a cream with no needles and unlimited e-visits with no contract, after confirming the full plan and FAA paperwork.

Here's the honest part. Male Excel's published at-home panel does not list a CBC. If having full blood counts built into your program is your top priority, Hone Premium is an option to check. But Male Excel offers a cream-based plan, and a testosterone-only topical plan may fit the FAA's topical-only path if all its conditions are met. That path doesn't list the 90-day CBC requirement the injection CACI path carries. Ask your prescriber what blood-count monitoring you need and ask your AME which dated records apply to your exact product and full regimen.

Three things to sort out before you start:

  • Ask about the thyroid component. Male Excel lists its testosterone plans "with Thyroid." Ask why any thyroid medicine is proposed and whether it is clinically needed. Any thyroid medicine goes on your FAA application.
  • Clarify Triclozene in writing. Its product page names enclomiphene, while its pricing page names clomiphene. The names are close, but the FAA treats them differently. Do not assume this oral blend qualifies for CACI. (Product page, pricing page)
  • Confirm the paperwork. Ask whether your Male Excel prescriber is a physician and will sign the FAA Status Summary. Male Excel also notes that DEA and state law may require an in-person exam for your plan.

Skip Male Excel if: it cannot confirm the blood tests and physician records your AME needs, you want FDA-approved products billed to insurance (check local care), or your history needs an in-person specialist. Hone Premium is another option to check for included CBCs, but its FAA paperwork and timing still need confirmation.

Does the proposed plan fit both your care needs and your AME's requirements? See Male Excel's current pricing and plans, and tell them you're a pilot on your first call. Resolve the medication, testing, and paperwork questions before paying.

Hone Health for pilots: Premium includes full blood counts

May fit: a pilot comparing physician visits and Premium's included full CBCs, after confirming the collection dates and FAA documentation with the clinic and AME.

Hone lists hematocrit and hemoglobin among the 50+ markers in Premium's initial panel. Its Premium lab schedule lists a full CBC at the initial test and months 3, 6, 9, and 12, then at months 18 and 24. Plus is different: its published TRT schedule includes hematocrit at confirmation and months 6, 12, and 18, not at every quarterly check. Both plans state that scheduled follow-up testing and consultations are included. Confirm the complete CBC report, collection date, and physician documentation before assuming the program meets your AME's needs. (Premium schedule, Plus schedule)

What to know first: Hone also offers enclomiphene, which the FAA does not accept. Its cream and troches are listed as compounded; ask whether your exact injection is an FDA-approved product or a compounded preparation. Hone doesn't take insurance for its service. It says you can ask to use a local pharmacy, though membership continues and it does not handle prior authorization. On day one, tell your Hone physician you're a pilot and need to review the full plan with your AME. A medicine appearing in the FAA table does not mean Hone offers it or that you need it. (Product and brand policy, local-pharmacy policy)

Skip Hone if: its available plan cannot meet your monitoring and record needs, or you need insurance-billed clinical care. If your proposed medicine is enclomiphene, resolve that conflict with your prescriber and AME before choosing any program. FDA-approved medication may be available through a local pharmacy, but that does not make Hone's service insurance-covered.

If Premium's included CBCs and physician visits fit the care you need, review Hone Health's Premium plan and pricing. Check its official state list and confirm FAA paperwork before paying. Treatment depends on clinical eligibility.

Local care: when specialist or insurance needs come first

Best for: people who need in-person specialist evaluation, have heart, clot, or prostate history that needs closer review, or want to check FDA-approved products and insurance coverage.

Local care lets you arrange an in-person exam with the specialists the FAA names and ask for the detailed note your case needs. The trade-offs are wait times, possible prior authorization, and a doctor who may not know FAA rules. Hand them the worksheet above. See TRT providers that take insurance and online vs. local TRT.

Programs built around enclomiphene aren't a pilot fit

If a clinic's main offer is enclomiphene, it's the wrong starting point for a certificated pilot under current FAA guidance. Clomiphene is the FAA-listed cousin. Whether either one makes sense for you is a medical question. See enclomiphene vs clomiphene.

What happens to online TRT after December 31, 2026?

The DEA and HHS temporary rules that let qualifying DEA-registered clinicians prescribe controlled substances like testosterone by telemedicine without a prior in-person evaluation run through December 31, 2026. Required conditions, state law, and licensing rules still apply (HHS telehealth guidance). Requirements after that date depend on the rules then in force. Ask the clinic how it would arrange any required in-person evaluation, and ask your AME what examination and documentation your case needs. We'll update this page when the rule changes.

Still deciding between online and local care? Explore general online TRT care options with TRT Provider Guide's Find My TRT Path tool. It doesn't assess FAA certification.


How we checked this page

Answer: We researched this guide on October 30, 2026 from current FAA documents, FDA and HHS announcements, Endocrine Society guidance, and each provider's own website. We kept FAA rules, provider claims, and our own judgment separate. We didn't enroll in any program or evaluate any pilot's case.

What we actually verified

Pilot TRT FAA paths, records and care comparisons table 16: What we actually verified
Item Details
Date checked October 30, 2026
FAA documents and their own dates Low T disposition table and CACI worksheet: April 29, 2026. Low T Status Summary: August 26, 2026. MedGuide: October 27, 2026. Low T AASI: PDF prints September 25, 2024; the archive records a September 24, 2025 revision. Clinical progress note guidance: September 25, 2024.
FAA facts confirmed Topical-only, CACI, and deferral paths. The 90-day CBC and note window. The 54% hematocrit line. The 7-day hCG and 14-day clomiphene trials. Enclomiphene not acceptable. Tamoxifen added. Yearly vs. per-exam paperwork. The general MedGuide wait and its exceptions. Items 17a, 18, and 19.
Other primary sources FDA (February 28, 2025 labeling), HHS (June 18, 2026 requested label changes), Endocrine Society guideline, HHS telehealth guidance (through December 31, 2026)
Provider-stated facts Male Excel and Hone Health pricing, tier-specific labs, medicines, prescriber descriptions, state lists, refill, cancellation, pharmacy, and record policies. We checked current plan and policy pages; we did not enroll, complete checkout, contact support, or verify an assigned clinician or pharmacy.
Our editorial judgments Conditional provider-fit guidance, leaving a paperwork buffer before the exam, and asking the AME to classify unclear products. First-year figures are our arithmetic from published prices, with exclusions stated.
What we could not confirm Whether each program's assigned physician will complete the FAA Status Summary and answer AME follow-up questions. Acceptance of a particular telehealth evaluation. Product-specific FAA classification for troches, nasal testosterone, gonadorelin, or non-Testopel pellets. A personal final quote, exact injectable product and dispensing pharmacy, or any individual pilot's outcome.

We compare programs using our published method, How We Review TRT Providers. It separates verified facts, provider-stated facts, customer reports, and our conclusions. We do not assign provider scores on this page. Our editorial standards explain the publication rules. Spot something out of date? Send it through our corrections page.


TRT for pilots: frequently asked questions

Answer: These questions cover testosterone and the FAA medical. Each short answer reflects FAA guidance checked October 30, 2026. Your own outcome still depends on your full record and your AME.

Is TRT disqualifying for an FAA medical?

Not automatically. Treated low testosterone has paths for AME issuance. Topical-only treatment needs the AME's assessment; other listed treatments can qualify through CACI with all criteria and other qualifications met, including a 90-day CBC and the right physician documentation.

Can I hold a first-class medical while on TRT?

Yes, if the applicable criteria and other requirements are met. The Low T guidance covers every class. First- and second-class pilots bring the CACI records once a year.

Do testosterone injections require special issuance?

Not automatically. Injectable testosterone is on the CACI list. Your AME can issue the same day if every criterion is met and you are otherwise qualified.

Is testosterone cream or gel automatically fine?

No. It's the simplest path, but your AME still has to find your treatment controlled, your medicines acceptable, and no symptoms that affect flying.

Can pilots take enclomiphene?

Not under current FAA Low T guidance. The FAA lists it as not acceptable. Clomiphene is listed, with a 14-day ground trial.

Can I fly on hCG?

hCG is listed for CACI review with a 7-day initial ground trial. Your AME must confirm the remaining requirements; the completed trial is not flight clearance.

What hematocrit does the FAA allow on TRT?

For the CACI path, 54% or lower on a CBC from the last 90 days. A higher number means your AME must defer.

Can I donate blood to lower my hematocrit and keep my medical?

Don't plan on it. The FAA lists treatment that requires phlebotomy as a deferral trigger. Your doctor should manage a high hematocrit.

Do I need to report testosterone cream on MedXPress?

Yes. Item 17a covers every medicine you currently use, including creams.

How long do I have to wait to fly after starting TRT?

The FAA's general MedGuide rule is a 48-hour wait for most new medicines, with shorter or longer waits for some. hCG and clomiphene have 7- and 14-day initial trials. Never fly with side effects that could affect flight safety. Confirm your wait with your AME.

Can an online TRT clinic fill out the FAA form?

Some may. The Status Summary's signature line asks for a physician. Ask the clinic before you pay. Then ask your AME whether a telehealth note will be accepted.

Does an FDA-approved product guarantee FAA acceptance?

No. FDA approval and FAA certification are separate decisions. The FAA looks at your condition, your full plan, and any side effects.

Can I use BasicMed while on TRT?

Low testosterone isn't one of the conditions that require a special issuance before BasicMed. You still list your medicines on the BasicMed checklist and follow 14 CFR 61.53. You must meet all other BasicMed eligibility and operating requirements.

What if my AME defers me?

Your file goes to the FAA for review and possible special issuance. A deferral isn't a denial. Ask your AME exactly what's missing and whether you can fly in the meantime.

Will TRT affect my fertility?

It can lower sperm production. If you want children, talk to a urologist or reproductive urologist before you start.

Does the FAA set a testosterone level or dose for pilots?

The cited Low T documents do not set one universal testosterone level or dose. They set certification criteria, not treatment targets. Your doctor manages your dose.

Can Find My TRT Path tell me whether I can fly?

No. It's an educational tool for sorting care options. It doesn't diagnose low testosterone or assess FAA certification. Your AME and the FAA do that.


Your next step

Print the worksheet. Take it to your treating doctor, then to your AME.

A current CBC, a completed Status Summary, and the exact treatment list give your AME the core records for a CACI review. Every criterion and other qualification requirement must still be met. Missing required information can lead to a deferral. Now you know where those boxes are.

Need an AME? Use the FAA's Find an Aviation Medical Examiner tool.

Still comparing online care options? Use our free Find My TRT Path tool.

For general care information only. It does not assess FAA certification or fitness to fly.


Sources

Not sure which TRT route fits you?

Find My TRT Path