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Does Enclomiphene Show Up on a Drug Test?

Does enclomiphene show up on a drug test? It isn't listed on published DOT urine or HHS federal workplace panels. Other employer panels vary. Anti-doping testing can detect it, and its drug class is prohibited under WADA rules. A prescription alone doesn't settle sports, military, or FAA permission.

By TRT Provider Guide · Last verified: October 2026 · Editorial research, not clinically reviewed.

Last updated: . Last verified: .

Best for: U.S. adults checking workplace, military, sports or FAA rules. Not for: predicting your test result, choosing treatment or getting medical clearance.

That last part is easy to miss. Keep reading if you wear a uniform, compete in a tested sport, or fly — your answer is in the table below, and it's probably not the one you expected.

Enclomiphene drug testing and permission rules table 1: Comparison
Your situation What do the published rules establish? Does a prescription settle it? Your next contact
DOT urine drug test (trucking, aviation safety jobs, rail, transit) Not listed. It isn't on the DOT urine panel, and labs can't add drugs to a DOT specimen. 1, 2 Panel exclusion does not settle separate reporting or fitness requirements Employer's program / Medical Review Officer
Federal agency workplace test (HHS) Not listed. The 2026 federal panels cover Schedule I and II drugs only. 4 Ask about the program's medication-reporting requirements Agency testing program
Private employer 5- or 10-panel Confirm the exact test ordered. Panels vary by lab and order code. 5 Keep it on hand anyway Employer's testing contact or lab
Military (active, Guard, Reserve, applicants) Confirm with your service testing program. We could not verify the complete current panel. 8 No. Enclomiphene is flagged by the DoD; a military provider must review it. 6, 7 Your military healthcare provider and service testing program
NCAA college sports Banned class. Hormone and metabolic modulators include SERMs such as clomiphene and related substances. 15 No. NCAA medical-exception preapproval rules apply. 29 Your athletics department
WADA-governed sport Prohibited at all times. Current WADA laboratory guidance explicitly covers enclomifene. 10, 13 No — an approved Therapeutic Use Exemption is needed. 12 Your anti-doping organization
FAA pilot medical certificate Not a drug-test question No. The FAA lists enclomiphene citrate as not acceptable. 18 Your Aviation Medical Examiner

Educational information, not medical advice. This page explains testing rules; it can't predict your result or decide whether you're allowed to take a medicine.

TRT Provider Guide is the independent decision resource for testosterone replacement therapy — helping U.S. adults understand how low testosterone is evaluated, compare online and local care models and providers, and choose the next step that fits their health needs, fertility plans, budget, state, and care preferences, with every material claim verified and dated.

Jump to your situation: Job test · Military · Sports · How long it stays detectable · Pilots and prescriptions · What to ask before your test

Does enclomiphene show up on a drug test for work?

Enclomiphene is not listed on the published DOT urine or HHS federal workplace panels. The federal DOT and HHS panels list specific controlled drugs — marijuana, cocaine, opioids, PCP, amphetamines and MDMA — and enclomiphene isn't one of them. Private employers can order different panels, so ask which test you're getting.

Here's what the two federal panels actually check, straight from the current rules:

Enclomiphene drug testing and permission rules table 2: Does enclomiphene show up on a drug test for work?
Federal panel What it tests for Enclomiphene?
DOT urine panel (49 CFR §40.85) Marijuana, cocaine, codeine/morphine, hydrocodone/hydromorphone, oxycodone/oxymorphone, heroin metabolite (6-AM), PCP, amphetamine/methamphetamine, MDMA/MDA 1 Not listed
HHS federal workplace panel (published March 13, 2026) The same drug classes, plus fentanyl. HHS describes these as panels of Schedule I and II drugs, with no changes from 2025. 4 Not listed

Two details make the DOT answer firmer than most people realize.

First, DOT specimens are off-limits for extra testing. The rule says an employer must not test a DOT specimen for additional drugs. 2 So nobody can quietly add enclomiphene to your DOT cup.

Second, DOT and company tests are separate. If your employer also runs its own non-DOT program, that's a different test with a different panel. 2 Ask which one you're taking.

What about a 5-panel or 10-panel from a private employer?

"5-panel" and "10-panel" don't tell you the exact test menu. Labs sell many panel combinations and order codes. Quest's most commonly requested five-panel screens for amphetamines, cocaine, marijuana, opiates and PCP. 5

We can't promise what's in every panel ever ordered. Nobody honestly can. If it matters, ask your employer's testing contact one question: "What's the exact panel or order code?"

Can enclomiphene cause a false positive?

We did not find an enclomiphene-specific false-positive report in the sources reviewed (checked October 30, 2026). That's not proof it's impossible. An unexpected result needs review of the actual assay and reported substance.

Under DOT rules, a Medical Review Officer (MRO) reviews confirmed positive results and must give you a chance to present a legitimate medical explanation for the results covered by §40.137. 3 Keep your prescription label and pharmacy details handy. A prescription for enclomiphene does not by itself explain a positive result for another substance.

The real job-test risk: "supplement" enclomiphene

Bought enclomiphene as a "testosterone booster" or "research chemical"? That's where trouble starts. The Department of Defense's Operation Supplement Safety (OPSS) says it's illegal to sell clomiphene or enclomiphene as a dietary supplement — yet products still list them and market them as testosterone boosters. 6 A product label cannot confirm whether undeclared drugs are present. OPSS warns that laboratory testing is needed to identify hidden ingredients. 8

Copy the questions for your workplace test →

Does enclomiphene show up on a military drug test?

A civilian workplace-panel answer does not settle a military testing question. OPSS flags enclomiphene in the DoD supplement framework and tells anyone with a prescription to see their military healthcare provider. A negative test is not permission to use it. 6

If you're already taking it, take a breath. You're not the first service member to ask this, and the next step is clear: a review with your military healthcare provider, starting now. Documentation supports that review; it does not guarantee permission.

What the routine military test covers

Military drug testing uses urine screening, sometimes followed by additional tests. OPSS directs questions about specific substances to the relevant service testing laboratory. 8 Public DoD descriptions of testing focus on illicit drugs and misused prescription drugs. Fentanyl was added in 2019. 9

We tried to pull the current full DoD testing instruction to confirm the complete panel. We couldn't access the full document, so we won't tell you enclomiphene is "never" tested. Ask your service testing program about the exact test and any additional testing. 8

Why a civilian prescription doesn't settle it

Here's the part that catches people. OPSS lists enclomiphene on the DoD Prohibited List as an unapproved drug, and notes it also falls under WADA's banned list. 6 DoD policy says service members won't use products on the prohibited dietary-supplement ingredients list unless a DoD health care provider authorizes it. 7

That list is about supplement ingredients. A prescribed medicine is a different situation — which is exactly why OPSS sends prescribed users to military medicine instead of giving a blanket yes or no. Its guidance is specific: talk with your military healthcare provider, use your installation's Medical Treatment Facility (MTF) when possible, and make sure every medication is in your military health record. 6

A prescription from a civilian telehealth clinic is information for that review. It isn't the review.

Your four-step plan

  1. Book your military primary care provider (PCM). Ask promptly how to handle your prescribed treatment while the review is pending.
  2. Bring the facts. Your bottle or label, the prescriber's name, the pharmacy, and any lab results.
  3. Ask directly: "Is this allowed for me and my duties, and can it go in my record?"
  4. Ask about alternatives if it isn't allowed — including evaluation through military urology or endocrinology.

Applying to join? Disclose your medications through the accession medical process. We can't predict enlistment, waiver, deployment or clearance outcomes, and neither can a recruiter or a Reddit thread.

Copy the questions for your military provider →

Is enclomiphene banned in sports?

Yes — under the World Anti-Doping Agency (WADA) Prohibited List, clomifene — the spelling WADA uses — sits in section S4.2, anti-estrogenic substances, and is prohibited at all times, in and out of competition. Enclomiphene is part of clomiphene, so it falls under the same section. A prescription alone doesn't make it allowed. 10, 6, 12

This one isn't a gray area. A few facts athletes need:

  • Banned 24/7. Clomifene is prohibited in and out of competition and classed as a specified substance under the 2026 list. 10, 11
  • WADA's lab guidance covers it directly. The current clomifene testing instructions explicitly include both isomers: zuclomifene and enclomifene. 13
  • The list isn't a spelling bee. OPSS confirms enclomiphene falls under WADA's Section 4 as a component of clomiphene. 6 An isolated isomer or a different spelling is not a loophole.
  • A prescription isn't permission. USADA explains that medical use requires a Therapeutic Use Exemption (TUE) — a separate approval through the anti-doping process. 12 Nobody can promise you'll get one.
  • College athletes too. The NCAA bans hormone and metabolic modulators, including SERMs such as clomiphene and related substances. 15 Its process is medical-exception preapproval, which your school must obtain before you participate in practice or competition while using these drugs. NCAA guidance says anti-estrogen treatment generally does not qualify for this approval in male student-athletes, with a possible exception for breast cancer or a history of it. A WADA TUE does not replace this NCAA process. 29

People still get caught. The International Testing Agency announced clomifene sanctions in 2026 involving athletes in wrestling, sambo and baseball; the samples in these cases were collected in 2024 or 2025. 11, 28, 30

What the 2026 clomifene reporting rule changes

WADA issued a new technical letter, effective January 1, 2026, on how labs report clomifene. The reason: tiny traces can come from contaminated poultry meat and eggs. It sets a minimum reporting level for the parent drug. 13 USADA's separate Premier Sports program, for example, uses a 0.10 ng/mL decision level for managing clomiphene findings as atypical findings that require investigation. 14

A low finding can still trigger a required investigation into whether contaminated food explains it. It does not create a "safe dose" for someone taking the drug. Low concentrations can also reflect previous drug use. 13

If you're subject to anti-doping testing, resolve the permission question before a treatment decision. Talk to your anti-doping organization and prescriber first. WADA publishes a new list every year that takes effect January 1 — check the current one.

See USADA's guidance on clomiphene and TUEs →

How long does enclomiphene stay in your system?

The research reviewed here does not establish a reliable detection window for enclomiphene-only products. In a controlled clomiphene study, the other isomer, zuclomiphene, stayed detectable in urine for four to more than eight months. That does not predict the detection window for enclomiphene alone or your particular test. 16

We'll be straight with you: we can't give you a countdown, and you should be suspicious of anyone who does. The studies reviewed do not establish how long enclomiphene alone would remain detectable on your specific test. Here's what has been measured, and what each finding can and can't tell you.

Enclomiphene drug testing and permission rules table 3: How long does enclomiphene stay in your system?
Evidence reviewed What it found What it doesn't tell you
Clomiphene, 50 mg daily for 30 days, 12 healthy men (Miller et al., 2019) The zuclomiphene part of clomiphene stayed detectable in urine for 121 to more than 261 days. 16 This was clomiphene, not an enclomiphene-only product.
Current WADA laboratory guidance Clomifene testing covers both isomers, including enclomifene. 13 It does not give an enclomiphene-only detection window.
A real sanction (case report) A futsal player tested positive 17 weeks after his last prescribed clomiphene dose and initially received a 4-year ban, reduced to 2 years on appeal. 17 One case, and it involved clomiphene.
Enclomiphene-only urine detection No reliable detection window established by the sources reviewed as of October 30, 2026. No personal clearance date can be calculated.

Two terms help here. An isomer is a form with the same atoms arranged differently. Clomiphene (the drug in Clomid) is a mix of two isomers: enclomiphene and zuclomiphene. 23 Enclomiphene itself clears faster than its partner molecule in clomiphene. 23 Most of the long tail in the studies comes from zuclomiphene. 16

So why not just say enclomiphene clears in days? Because a half-life — how long it takes for half a drug to leave your blood — is not a detection window. Urine detection can persist after blood levels drop. 16 And FDA does not verify the safety, effectiveness or quality of compounded drugs before they are marketed. 22

Our conclusion, plainly: clomiphene findings cannot give you an enclomiphene-only countdown. If you're under anti-doping rules, resolve permission with your governing organization. For employment testing, confirm the actual panel rather than relying on a clearance estimate.

Does a prescription mean enclomiphene is allowed?

It depends on who's asking. For a DOT test, the MRO decides whether the documentation provides a legitimate medical explanation for the reported result. Military authorization, sports exemptions and FAA medical certification are separate decisions. 3, 6, 12, 18

In the military, you also need a DoD provider's review. In tested sport, the governing program's exemption rules apply. And for pilots, the FAA says enclomiphene citrate is not acceptable — no negative drug test fixes that.

Enclomiphene drug testing and permission rules table 4: Does a prescription mean enclomiphene is allowed?
Where you are What a prescription does What review is needed
DOT workplace test Provides information for the MRO's review 3 Review of the reported substance and your label, prescriber and pharmacy details
Military Starts the conversation Military provider review, any required authorization, and an updated health record 6, 7
Tested sport Nothing on its own 12, 29 Your governing program's exemption process: a TUE or NCAA medical-exception preapproval, as applicable
FAA medical certificate Nothing for enclomiphene 18 Review with your prescriber and AME; a different medicine does not automatically mean clearance

The pilot surprise

This is the finding that surprised us most. The FAA's guidance for Aviation Medical Examiners (AMEs) on low testosterone, updated April 29, 2026, sorts treatments into groups. Pilots using some testosterone treatments or clomiphene citrate may qualify for issuance through a structured worksheet process if all its criteria are met and they are otherwise qualified. But the same document says, in plain terms: "Use of enclomiphene citrate is NOT acceptable." 18

Read that again if you fly. Clomid-type clomiphene has a path. Enclomiphene doesn't — at least not under this guidance.

We're not telling any pilot to stop or switch a medicine. Talk to your prescriber and your AME together before your next exam.

Is enclomiphene a steroid or a controlled substance?

No to both — enclomiphene is a selective estrogen receptor modulator (SERM), not an anabolic steroid, and it isn't on the DEA's controlled-substance schedules. It also isn't FDA-approved. In the U.S., it's made by compounding pharmacies, which is a different regulatory category from an FDA-approved drug. 19, 20, 22, 24

Lawfully compounded enclomiphene requires a valid prescription; being nonscheduled does not make it an over-the-counter supplement. 6

A SERM changes how estrogen signals work in different parts of the body. In men, enclomiphene blocks estrogen's "slow down" signal in the brain. The brain answers by sending more LH (luteinizing hormone), which tells the testicles to make testosterone, and FSH (follicle-stimulating hormone), which supports sperm production. Your body makes the testosterone. No testosterone is added from outside. 24

Here's how enclomiphene, clomiphene and testosterone differ:

Enclomiphene drug testing and permission rules table 5: Is enclomiphene a steroid or a controlled substance?
Question Enclomiphene Clomiphene (Clomid) Testosterone
What it is SERM; one isomer of clomiphene SERM; mix of enclomiphene + zuclomiphene 23 Hormone; anabolic steroid
Controlled substance? No No Schedule III 19
FDA-approved? No — no approved product 20, 24 Yes, for ovulation problems in women; use in men is off-label 23 Yes, specific products; compounded versions are not 22, 36
On the published DOT urine/HHS federal workplace panels? Not listed 1, 4 Not listed 1, 4 Not listed 1, 4
WADA Banned, S4.2 10, 6 Banned, S4.2 10 Banned, S1 anabolic agents 10
FAA (low-T guidance) Not acceptable 18 Conditional worksheet path 18 Conditional issue/worksheet path, depending on form 18

Where enclomiphene stands with the FDA in 2026

  • Never approved. FDA records show the drug's developer received a Complete Response Letter — a "not approved in its current form" decision — in December 2015. 24
  • Advisory committee voted against it. In June 2022, FDA's Pharmacy Compounding Advisory Committee voted 4 in favor, 8 against adding enclomiphene citrate to the 503A Bulks List. 21 That was advice, not a ban.
  • Still "under evaluation." FDA's May 14, 2026 list keeps enclomiphene citrate in Category 1, meaning it remains under evaluation. 20 Under FDA's interim policy, the agency does not intend to take enforcement action when all the policy's conditions are met. 31 Category 1 is not FDA approval or blanket permission to compound it.
  • Compounded drugs aren't FDA-approved. FDA doesn't review compounded drugs for safety, effectiveness or quality before they're marketed. 22

None of this changes which drugs are listed on the published DOT urine and HHS federal workplace panels. Testing rules, sports rules and military permission remain separate questions.

What should you confirm before your drug test?

Start by finding out which program ordered your test and who handles medical questions. Then keep your exact medication details ready, and ask whether a separate permission review applies. The questions below get you an answer about your situation, not the internet's average.

We built this worksheet from the differences in the rules above. Copy it, print it, or screenshot it. You don't need to send it to us.

Questions for any testing program

  1. Which program is this — DOT, federal agency, my employer's own program, military, sports, or something else?
  2. What's the exact panel or order code, and where can I read the policy?
  3. Who reviews medication questions, and how do I reach them?
  4. What prescription or pharmacy information do you need from me, and how should I send it?
  5. Is there a separate medication-permission, duty, exemption or medical-certification step?
  6. Can you point me to the written rule, so I can note the date of your answer?

Add the questions that fit you

Enclomiphene drug testing and permission rules table 6: Add the questions that fit you
Your situation Ask this too
Job or DOT "Is this only the DOT test, or is there a separate company test?" · "Who handles medication information and any fitness-for-duty review?"
Military "Please review this exact product against my service and duty requirements." · "How should this prescription be recorded in my military health record?"
Tested sport "Which prohibited list and TUE or NCAA medical-exception rules apply to me?" · "What do I need to submit, and before when?"
Pilot "How does the FAA's enclomiphene guidance affect my medical certificate?" · "What should my prescriber and AME discuss?"
Not sure "Who ordered this test, under which policy?" · "Who is the right contact for a medication question?"

Keep a private record

Enclomiphene drug testing and permission rules table 7: Keep a private record
Record Fill in
Testing program
Panel or order code
Medication name and full ingredient list
Prescriber and pharmacy
Who you spoke to, and their role
Written policy and its date
Documents requested
Any separate approval still needed
Date of the answer

Don't change a prescribed medicine on your own to "beat" a test. For military, sport or flying, make that decision with your prescriber and the right authority.

Thinking about starting enclomiphene?

If you've confirmed your workplace panel, the next question is whether enclomiphene fits your care needs. It works by boosting your own testosterone signal, and it has been studied in selected men with secondary hypogonadism — low testosterone linked to the brain's hormone signals. Fertility plans and how low testosterone was confirmed matter more than the drug test. 24, 26

Skip this section if you're military, a tested athlete, or a pilot. Your answer is above, and it starts with your provider, anti-doping organization or AME — not a subscription.

For everyone else, two checks come first:

  • Confirm the diagnosis properly. The Endocrine Society says diagnosing low testosterone needs symptoms or signs plus consistently low results, confirmed with repeat morning fasting total-testosterone tests using accurate assays — not one number. 25 See what TRT blood tests involve.
  • Put fertility on the table early. Testosterone therapy can suppress sperm production, and the Endocrine Society recommends against it for men planning fertility in the near term. 25 In pooled trials of selected men with functional or secondary hypogonadism, sperm concentration with clomiphene or enclomiphene was higher than with testosterone gel, but not statistically different from placebo. 26 That's less suppression than testosterone in those studies — not a promise of fertility. Trying to conceive soon? Start with a reproductive urologist. See TRT and fertility.

The right TRT provider is not the same for every person — it depends on whether low testosterone has been properly evaluated, your symptoms and health history, your fertility plans, your state, your insurance or cash-pay preference, your treatment-format preference, your budget, and whether online or in-person care is the better starting point. Some situations belong with primary care, urology, endocrinology, reproductive urology, or urgent or emergency care when the symptoms warrant it. Because a general answer cannot resolve those for you, discuss the right care route with a clinician. For educational information about online programs, use TRT Provider Guide's Find My TRT Path tool to explore programs and questions to ask before you pay.

What enclomiphene offers actually cost

Affiliate disclosure: Taurus Meds and Male Excel are commercial partners of TRT Provider Guide. We may earn a commission through provider links. That doesn't change what we verify or who we tell to look elsewhere. Read our affiliate disclosure.

We compared published enclomiphene offers in September 2026, and the sticker prices hide a lot. 27 We rechecked the provider-stated figures below on October 30, 2026. A few examples from that research:

  • Taurus Meds advertises enclomiphene at $149/month after a $49 starting offer that includes a lab test and video consult. 32, 39 A 12-month model is $1,837 before any extra fee: $49 + (12 × $149). Its general terms list a $17.99 fee per billing period unless other terms apply at purchase; whether that fee applies to this offer still needs a written answer. 33 See what the Taurus offer includes.
  • Hone Health lists enclomiphene from $42/month — but that's medication only. Its required Plus membership is $135/month, so the real starting cost is $177/month plus a $45 first test. At those starting prices, 12 months total $2,169: $45 + (12 × $177). Hone says follow-up labs, consultations and shipping are included; the prescribed medication cost can vary. 34
  • Male Excel's oral product, Triclozene, is a blend that includes thyroid hormone — not plain enclomiphene. It's our partner, and we'd still rather tell you that than sell you something you didn't search for. Its pricing page names clomiphene in the blend, while its product page describes enclomiphene; confirm the exact formula in writing. 35, 37

Hone labels its enclomiphene as compounded, and Male Excel labels Triclozene an oral compound. 34, 35 Taurus's public offer does not identify the exact finished formula or dispensing pharmacy. 32 None of these pages guarantees a prescription. If you want the published cost models, ingredient disclosures and cancellation terms side by side — including what's still unresolved — it's all in one place.

Compare enclomiphene offers by full first-year cost →

Still not sure enclomiphene is even your route? Use Find My TRT Path to see which online TRT program fits your situation → It takes about a minute, needs no email, and its privacy notice says your answers stay in your browser tab. It's educational — it doesn't diagnose low testosterone or guarantee a prescription.

How did we verify this page?

We checked the official rules ourselves on October 30, 2026 — DOT and HHS panels, OPSS and DoD policy, WADA, USADA and NCAA guidance, the FAA's current low-testosterone document, FDA records and the primary research. We kept what each source proves separate from what still depends on your program.

What we actually verified — October 30, 2026

  • Checked directly: DOT §§40.13, 40.85 and 40.137; the HHS federal panels published March 13, 2026; OPSS's enclomiphene guidance; DoD Instruction 6130.06 through an official Marine Corps copy; the 2026 WADA S4.2 list and clomifene laboratory instructions; USADA's clomiphene guidance; NCAA banned-substance and medical-exception rules; the FAA disposition table updated April 29, 2026; FDA compounding information and interim policy; and the primary excretion research.
  • Confirmed: The specific statements we attribute to those sources on this page.
  • Couldn't confirm: The full current DoD testing-panel table (the document wasn't accessible), every private employer's panel, any enclomiphene-only detection window, and individual permissions or exemptions.
  • What we didn't do: We didn't test any specimens, enroll with any provider, or contact any authority on a reader's behalf.
  • Provider-stated facts: We rechecked the quoted prices and formula disclosures against Taurus Meds, Hone Health and Male Excel's official pages on October 30, 2026. We did not complete checkout or obtain a written answer about Taurus's extra fee or Male Excel's conflicting formula descriptions.

Our method for provider research is How We Review TRT Providers. It separates verified facts, provider statements, customer reports and our own conclusions. It is not a numeric medical score. See our editorial standards and corrections policy.

What else should you know about enclomiphene drug testing?

Your test panel and your program's permission rules are separate questions. These frequently asked questions cover the distinctions that change the answer; your testing contact or clinician handles your individual result and treatment decisions.

Does enclomiphene show up on a 10-panel drug test?

A "10-panel" label alone does not establish the exact analytes. Panels vary by lab and order code, so ask your employer which test it ordered and request the analyte list. 5

Does enclomiphene show up on a DOT drug test?

No. It isn't on the DOT urine panel, and DOT rules prohibit testing a DOT specimen for additional drugs. 1, 2

Does enclomiphene show up on a military drug test?

We could not verify the complete current military panel, so ask your service testing program about the exact test. OPSS flags enclomiphene in the DoD supplement framework and directs prescribed users to their military healthcare provider. 6, 8

Can you take enclomiphene in the military?

Your military healthcare provider must review the exact product for your service and duties, including any required authorization. Recording a prescription is not automatic permission, and a civilian prescription alone doesn't settle it. 6, 7

Is enclomiphene banned by WADA?

Yes. It falls under S4.2, anti-estrogenic substances, which are prohibited at all times. A prescription isn't enough; you'd need an approved TUE. 10, 6, 12

Is enclomiphene banned by the NCAA?

Yes. The NCAA's hormone and metabolic modulator class includes SERMs such as clomiphene and related substances. 15 Its medical-exception preapproval process goes through your school, and NCAA guidance says anti-estrogen treatment generally does not qualify in male student-athletes, with a possible exception for breast cancer or a history of it. 29

How long does enclomiphene stay in your urine?

The sources reviewed do not establish a reliable window for enclomiphene alone. In a clomiphene study, zuclomiphene stayed detectable for 121 to more than 261 days. 16 That does not predict an enclomiphene-only detection window.

Can enclomiphene cause a false positive?

We did not find an enclomiphene-specific false-positive report in the sources reviewed as of October 30, 2026. That does not rule it out on every assay. For DOT results covered by §40.137, the MRO must give you a chance to present a legitimate medical explanation; enclomiphene alone does not explain a positive for another substance. 3

Is enclomiphene a steroid?

No. It's a SERM that signals your body to make more of its own testosterone. It's not an anabolic steroid and not a controlled substance. 19, 24

Is enclomiphene FDA-approved?

No. There's no FDA-approved enclomiphene product. It's available through compounding pharmacies, and compounded drugs aren't FDA-approved. 6, 20, 22

Does Clomid show up on a drug test?

Clomiphene is not listed on the published DOT urine or HHS federal workplace panels; other employer panels vary. 1, 4, 5 It is banned under WADA and NCAA rules and flagged by OPSS for service members. 6, 10, 15 One difference: the FAA's guidance gives clomiphene citrate a conditional worksheet path, while enclomiphene citrate is listed as not acceptable. 18

Can pilots take enclomiphene?

Not under the FAA's current low-testosterone guidance, which lists enclomiphene citrate as not acceptable. Talk to your AME and prescriber before your exam. 18

Should I stop enclomiphene before a drug test?

Don't change a prescribed medicine on your own to get through a test. For military, sport or flying, decide with your prescriber and the right authority.

What if I already got an unexpected result?

Contact the designated reviewer right away and follow their deadlines. Ask which substance was reported, whether it was a screen or a confirmed result, and how to submit your medication records. 3

Still not sure which online TRT program fits your situation? Use our free Find My TRT Path tool.

Last verified: October 2026. Testing rules, sports lists and FDA status change. The rules and provider-stated prices cited above were checked on October 30, 2026; unresolved details are identified where they matter. Spot something out of date? Send a correction.

Educational information, not medical advice. This page has not been medically reviewed. It can't diagnose low testosterone, predict a test result, or decide whether you're allowed to take a medicine. If you have chest pain, sudden shortness of breath, sudden vision loss or another urgent symptom, seek emergency care. 38

Sources

All sources checked October 30, 2026. Provider prices and product descriptions are provider-stated; the underlying documents retain the dates shown below.

  1. U.S. Department of Transportation — 49 CFR §40.85, urine drug test analytes and cutoffs
  2. U.S. Department of Transportation — 49 CFR §40.13, DOT and non-DOT tests; no additional drugs on DOT specimens
  3. U.S. Department of Transportation — 49 CFR §40.137, MRO verification and legitimate medical explanations
  4. HHS/SAMHSA — Mandatory Guidelines for Federal Workplace Drug Testing Programs: Authorized Testing Panels, 91 FR 12308, March 13, 2026
  5. Quest Diagnostics — Urine testing panels and cutoffs for employers
  6. Operation Supplement Safety (DoD) — Clomiphene and Enclomiphene: Drugs, Not Dietary Supplements; content current as of January 12, 2026
  7. DoD Instruction 6130.06 — Use of Dietary Supplements in the DoD, §1.2(c); official Marine Corps copy
  8. Operation Supplement Safety (DoD) — Drug testing and dietary supplements
  9. Armed Forces Medical Examiner System, via DVIDS — DoD adds fentanyl to drug testing panel; November 21, 2019
  10. World Anti-Doping Agency — 2026 Prohibited List, effective January 1, 2026
  11. International Testing Agency — Sanction notice citing clomifene under S4.2, prohibited at all times, specified substance; March 4, 2026
  12. USADA — Substance profile: what athletes need to know about clomiphene
  13. World Anti-Doping Agency — Technical Letter TL26, clomifene analysis and reporting, effective January 1, 2026
  14. USADA — Premier Sports Prohibited List 2026, clomiphene decision concentration level and atypical-finding procedure
  15. NCAA — Banned substances; hormone and metabolic modulators
  16. Miller GD et al. — Hypothalamic-pituitary-testicular axis effects and urinary detection following clomiphene administration in males. J Clin Endocrinol Metab. 2019;104(3):906–914
  17. Asian Journal of Sports Medicine — Medical treatment in men with infertility can be misinterpreted as doping practice: a case report
  18. FAA — Low Testosterone (Hypogonadism) disposition table for AMEs, updated April 29, 2026
  19. DEA — Controlled substances, alphabetical list
  20. FDA — Bulk drug substances nominated for use in compounding under section 503A; May 14, 2026 list
  21. FDA — Pharmacy Compounding Advisory Committee final minutes, June 8, 2022
  22. FDA — Compounding and the FDA: Questions and Answers
  23. DailyMed — Clomid (clomiphene citrate) prescribing information
  24. FDA — Pharmacy Compounding Advisory Committee briefing materials on enclomiphene citrate, June 8, 2022
  25. Endocrine Society — Testosterone Therapy for Hypogonadism clinical practice guideline
  26. Hohl A et al. — Clomiphene or enclomiphene citrate for male hypogonadism: systematic review and meta-analysis. Arch Endocrinol Metab. 2025;69(5):e250093
  27. TRT Provider Guide — Best enclomiphene providers compared; September 2026 comparison, with prices on this page rechecked October 30, 2026
  28. International Testing Agency — Baseball player Yadir Drake Dominguez sanctioned with a two-year period of ineligibility; February 25, 2026
  29. NCAA — Medical exceptions; preapproval requirements and hypogonadism guidance
  30. International Testing Agency — Sambo athlete Khakimjon Ismoilov accepts a two-year ban; January 30, 2026
  31. FDA — Interim Policy on Compounding Using Bulk Drug Substances Under Section 503A; January 2025, §III.A
  32. Taurus Meds — Enclomiphene offer and starting lab/consult price; provider-stated information checked October 30, 2026
  33. Taurus Meds — Terms and Conditions, §28; per-billing-period fee
  34. Hone Health — Hone Plus membership, medication prices and included services; updated September 29, 2026
  35. Male Excel — HRT costs and Triclozene formula; provider-stated information checked October 30, 2026
  36. FDA — Testosterone Information; approved products and indications
  37. Male Excel — Oral testosterone-booster product page; provider-stated formula checked October 30, 2026
  38. MedlinePlus — Recognizing medical emergencies
  39. Taurus Meds — Starting testosterone blood test and included video consultation; provider-stated information checked October 30, 2026

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