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Oral Testosterone (2026): Which TRT Pills Are Real, How Well They Work, and Who Should Take Them

Oral testosterone is real prescription testosterone you swallow. Kyzatrex, Jatenzo and Tlando are three FDA-approved brands for testosterone replacement therapy (TRT). In the main study analyses, 80% to 88% of men with confirmed low testosterone reached normal average levels. These pills require food and monitoring. They can raise blood pressure and lower sperm count.

Henry advertises Kyzatrex at $179 a month, including visits, labs and medicine. That is a provider-stated bundle, with quantity and cancellation limits explained below. 21 32

This guide covers U.S. adult men being evaluated or treated for low testosterone.

But here's what most pages miss. Some products sold as "testosterone pills" contain no testosterone at all. And Kyzatrex, Jatenzo and Tlando each need a monitoring blood test at a different interval after the morning dose. Get that wrong and your numbers can mislead your doctor. We'll show you both below.

That answer changes if:

  • Your low testosterone hasn't been assessed from symptoms or signs and at least two early-morning blood tests.
  • You want to have kids now or in the future.
  • Your blood pressure isn't under control.
  • The "pill" you saw is enclomiphene, clomiphene or a supplement. Those aren't testosterone.
Oral testosterone products, monitoring, care routes and costs table 1: Comparison
A testosterone pill may fit you if… Look elsewhere first if…
A clinician has confirmed low testosterone and found oral TRT appropriate You haven't had proper testing yet
You want to avoid testosterone injections and gel You're trying to conceive soon
You can take a dose with breakfast and dinner Your blood pressure is high or unknown
Your blood pressure is controlled The complete pill-and-care quote is beyond your budget

TRT Provider Guide is the independent decision resource for testosterone replacement therapy — helping U.S. adults understand how low testosterone is evaluated, compare online and local care models and providers, and choose the next step that fits their health needs, fertility plans, budget, state, and care preferences, with every material claim verified and dated.

Three modern FDA-approved testosterone brands at a glance

Oral testosterone products, monitoring, care routes and costs table 2: Three modern FDA-approved testosterone brands at a glance
Kyzatrex Jatenzo Tlando
Maker Marius Pharmaceuticals Tolmar Verity Pharmaceuticals
FDA approval July 27, 2022 March 27, 2019 March 28, 2022
Dose can be adjusted? Yes Yes No — one fixed dose
Taken Usually twice daily with food; lowest prescribed regimen is once daily Twice daily with food Twice daily with food
Reached normal average levels in main study 88% 87% 80%
Access routes checked Online services or your doctor Your doctor and pharmacy program Your doctor and pharmacy program
Our deeper guide Kyzatrex reviews Jatenzo reviews Tlando reviews

Study results come from different trials with different designs. They aren't a head-to-head contest. 1 2 3 4 5 6

What we actually verified (October 23, 2026)

  • Checked against primary sources: the current FDA labels for all three pills on DailyMed (Kyzatrex revised August 2026, Jatenzo revised September 2025, Tlando label current as of February 2026); the HHS/FDA labeling request of June 18, 2026; the Endocrine Society's July 16, 2026 statement; the AUA testosterone guideline; and the federal telemedicine rule.
  • Provider-stated (their words, not tested by us): prices, what's included, age and state limits, and cancellation terms from Henry, Hims, Male Excel, Taurus Meds, Hone Health and the three drugmakers.
  • Not confirmed: your personal price, your insurance coverage, pharmacy stock in your area, and which online services treat patients in your state.
  • What we did not do: take these medicines, buy them, or have this article reviewed by a clinician. This is an evidence and policy review. Our process is described in How We Review TRT Providers.

The right TRT provider is not the same for every person — it depends on whether low testosterone has been properly evaluated, your symptoms and health history, your fertility plans, your state, your insurance or cash-pay preference, your treatment-format preference, your budget, and whether online or in-person care is the better starting point. Some situations belong with primary care, urology, endocrinology, reproductive urology, or urgent or emergency care when the symptoms warrant it. Because a general answer cannot resolve those for you, use TRT Provider Guide's Find My TRT Path tool as an educational starting point, then use the questions below with a clinician before you pay.

Use Find My TRT Path → Free and educational. It doesn't diagnose low testosterone, decide eligibility, or guarantee a prescription. Privacy policy.


Is there an FDA-approved testosterone pill?

Yes, Kyzatrex, Jatenzo and Tlando are FDA-approved testosterone capsules for adult men with low testosterone due to certain medical conditions. An older pill, methyltestosterone, is also FDA-approved, but it carries serious liver warnings, and the American Urological Association says doctors should not prescribe it. Enclomiphene, clomiphene and supplements are not testosterone. 1 2 3 7 8

You'll often read that "only three testosterone pills are FDA-approved." That's close, but not quite right. Methitest's methyltestosterone label is listed on DailyMed, and FDA records confirm its approval. It's a much older type of pill. Its label warns that long-term use can cause serious liver problems. The AUA guideline says clinicians should not prescribe this kind of "alkylated" oral testosterone. 7 8

So the honest answer is: the three modern brands compared here are Kyzatrex, Jatenzo and Tlando. Older methyltestosterone has serious liver warnings.

Then there's everything else sold as a "testosterone pill." Here is how the main types differ.

The Pill Reality Check: what that "testosterone pill" really is

Oral testosterone products, monitoring, care routes and costs table 3: The Pill Reality Check: what that "testosterone pill" really is
What's being sold Examples Is it testosterone? FDA-approved to treat low T in men? Needs a prescription? What to know
Modern testosterone capsules Kyzatrex, Jatenzo, Tlando Yes Yes Yes (Schedule III) The real oral TRT. Labels say they aren't known to cause the liver damage linked to old pills.
Old alkylated pill Methyltestosterone (Methitest) Yes (a modified form) Yes, decades ago Yes (Schedule III) Label warns of serious liver problems. AUA says don't prescribe it.
Compounded testosterone troches Hone Health's troche, compounding pharmacies Yes No Yes (Schedule III) Dissolves in the mouth. Compounded drugs are not FDA-approved. AUA prefers factory-made products when possible.
Pills that make your body produce more testosterone Enclomiphene (Hims, Taurus Meds, Male Excel's Triclozene); clomiphene No No. Enclomiphene isn't FDA-approved. Clomiphene is approved for certain fertility problems in women and used off-label in men. Yes Not TRT. A different tool for some men, especially those who want to protect sperm production.
"Testosterone boosters" Over-the-counter supplements Not approved testosterone treatment; hidden drugs are possible No No Not a treatment for low testosterone. The FDA has warned that some bodybuilding "supplements" contain hidden steroids.

1 2 3 7 8 9 10 11 12

Here's a quick rule. If a "testosterone pill" ships without a prescription, it either isn't testosterone or it's being sold illegally. Testosterone is a Schedule III controlled substance in the U.S. Schedule III means it has accepted medical uses but can be misused, so federal law requires a valid prescription. 1

Two words you'll see a lot:

  • FDA-approved means the FDA reviewed the drug's safety, effectiveness and manufacturing before it was sold.
  • Compounded means a pharmacist or clinician combined or changed a medicine to meet a patient's medical needs. The FDA doesn't approve compounded drugs, and a compounded product is not a generic version of an approved one. 9

How do Kyzatrex, Jatenzo and Tlando compare?

All three contain testosterone undecanoate and require food; Kyzatrex's lowest prescribed regimen is once daily, while the other regimens are twice daily. Kyzatrex and Jatenzo let your clinician raise or lower the dose based on blood tests. Tlando uses a fixed regimen, and your clinician uses the monitoring result to decide whether to continue or stop it. 1 2 3

Side-by-side, straight from the FDA labels

Oral testosterone products, monitoring, care routes and costs table 4: Side-by-side, straight from the FDA labels
Kyzatrex Jatenzo Tlando
How dosing works Clinician adjusts up or down Clinician adjusts up or down Fixed regimen; clinician decides whether to continue or stop
Capsule strengths 50, 100, 150, 200 mg 158, 198, 237 mg 112.5 mg
With food? Yes Yes Yes
Main study result 88% reached normal average levels (122 of 139 men in the efficacy analysis, day 90) 87% (145 of 166 men, about 4 months) 80% (about day 24, 95 men)
24-hour blood pressure change (average) +1.7 / +0.6 mmHg at 4 months +4.9 / +2.5 mmHg at about 4.5 months +4.3 / +1.4 mmHg at about 4 months
Blood pressure boxed warning Removed July 2025 Removed July 2025 Removed July 2025
Older-adult evidence Limited; label contains conflicting age information No patients over 65 in main study 16 of 95 patients were over 65
Can you swap it for another brand? No — label says not substitutable Not without a new prescription No — label says not substitutable

Different studies, different designs. Use this to understand each drug, not to crown a winner. 1 2 3 4 5 6

Kyzatrex's geriatric section says no participants were 65 or older, but its study section gives an age range of 22–66. We could not resolve that discrepancy. 1

The Blood-Test Clock: same drug, different timing

This one surprises people.

To diagnose low testosterone, you get tested early in the morning. But once you're on a pill, the monitoring test is timed to your dose. And each brand uses a different clock. 1 2 3

Oral testosterone products, monitoring, care routes and costs table 5: The Blood-Test Clock: same drug, different timing
Pill First testosterone check Blood draw timing If you take your morning dose at 7 a.m. What the result decides
Kyzatrex 7 days after starting or after a dose change 3–5 hours after the morning dose Lab visit between 10 a.m. and noon Dose goes up, down or stays
Jatenzo At least 7 days after starting or after a dose change 6 hours after the morning dose Lab visit around 1 p.m. Dose goes up, down or stays
Tlando 3–4 weeks after starting 8–9 hours after the morning dose Lab visit between 3 and 4 p.m. Clinician decides whether to continue or stop

Why does this matter? A draw at the wrong hour can make your level look too high or too low. That can lead to a dose change you didn't need. Tell the lab which pill you take and what time you took it. Your clinician gives the final instructions.

Which pill fits which person?

  • Want to explore online prescribing? Kyzatrex is offered by Henry and Hims, subject to clinical and state requirements. 18 21 → Kyzatrex reviews
  • Prefer a fixed regimen and have a willing doctor? Tlando. → Tlando reviews
  • Have commercial insurance that covers Jatenzo? Jatenzo. → Jatenzo reviews
  • Already treated for high blood pressure? Talk to your doctor first. The labels show bigger average rises in men on blood pressure medicine. 1 2
  • 65 or older? Older-adult evidence is limited. Jatenzo's main study included no men over 65; Kyzatrex's label contains conflicting age information. Your own doctor may be the better starting point. 1 2

Ready to see who actually prescribes these pills? Compare the care routes, advertised costs and limits below.

Compare oral TRT care and cost routes →


Does oral testosterone work as well as injections?

In their main studies, 80% to 88% of men in the efficacy analyses reached normal average testosterone levels on these pills. These label studies do not establish that the pills work as well as injections. Those percentages measure blood levels, not symptom relief; results for energy, mood and sex drive vary from person to person. 1 2 3 13

Let's be clear about what the numbers mean. "Reached normal levels" means the average testosterone over 24 hours landed in the study's normal range. That's a lab result. It doesn't promise you'll feel different.

Here's what each format really trades:

Oral testosterone products, monitoring, care routes and costs table 6: Does oral testosterone work as well as injections?
Pills Injections Gels and creams
How often Usually twice daily with food; Kyzatrex has a once-daily exception Schedule depends on the prescribed product Schedule depends on the prescribed product
Testosterone injections No Yes No
Skin-transfer risk to partner or kids None None Yes, from skin contact
Blood tests and BP checks Required Required Required
Fertility concern Yes Yes Yes

1 2 3 14

A pill isn't the simplest way to take testosterone. It's the most convenient for some people. For most of these regimens, two doses a day, always with food, is a real routine. If your clinician prescribes a weekly injection, that may be easier to fit into your day.

But if testosterone injections or gel transfer are the reason you've put this off for years, a pill removes that wall.

Want the deeper version? See oral testosterone vs injections and testosterone cream vs oral testosterone.

How long does oral testosterone take to work?

Your blood level is checked within the first 1 to 4 weeks, depending on the pill. How you feel is a different question. There's no label timeline for symptoms, and they vary by symptom and by person. Ask your clinician when you'll review whether it's working, not just whether your number is in range.


Is oral testosterone safe? Blood pressure, liver and other risks

For men with confirmed low testosterone and regular monitoring, the modern pills have a known list of risks. The main ones are a rise in blood pressure, a higher red blood cell count, prostate changes and lower sperm production. The liver damage tied to old testosterone pills isn't known to happen with these, but you should still report yellow skin or dark urine. 1 2 3

Does oral testosterone raise blood pressure?

Yes. The average rise differed across the studies. All three labels list blood pressure increases as a warning. The FDA removed the boxed warning in July 2025, but the warning itself stayed. 1 2 3

  • Jatenzo: average 24-hour rise of 4.9/2.5 mmHg. In men already on blood pressure medicine, 5.4/3.2. About 7% of men started or increased blood pressure medicine during the study. 2
  • Tlando: average rise of 4.3/1.4 mmHg. 3
  • Kyzatrex: average rise of 1.7/0.6 mmHg at 4 months; 3.4 mmHg systolic in men already treated for high blood pressure. 1

None of the labels recommend these pills for uncontrolled high blood pressure. Some cold and pain medicines also raise blood pressure, so tell your clinician everything you take. 1 2 3

Is oral testosterone bad for your liver?

The "testosterone pills wreck your liver" story comes from methyltestosterone. That pill's label warns about serious liver injury. 7

The modern capsules are different. Their labels say they are not the "17-alpha-alkyl" type and are not known to cause those liver effects. They still tell you to report nausea, yellow skin or eyes, dark urine or right-side belly pain right away. 1 2

Other risks to know

  • Higher red blood cell count (hematocrit). Hematocrit is the share of your blood made of red cells. Too high raises clot risk. Labels call for a check before treatment, then about every 3 months for Kyzatrex and Jatenzo; Tlando calls for checks every 3 months in the first year and every 6 months after that. 1 2 3
  • Blood clots. In the large TRAVERSE study of testosterone gel, clots in the lungs were more common than with placebo (0.9% vs 0.5%). 2 15
  • Heart attack and stroke. TRAVERSE found major cardiovascular events were similar with gel and placebo (7.0% vs 7.3%). That study used gel, not pills. 2 15
  • Prostate. Your clinician should assess prostate risk before and during treatment, with PSA testing based on your age, risk and the product label. PSA (prostate-specific antigen) is a blood test used to screen for prostate problems. 1 2 8
  • Also listed: swelling, worse sleep apnea, breast enlargement, cholesterol changes. Jatenzo's label also lists depression and suicidal thoughts reported in trials. 1 2

Call 911 now for chest pain, trouble breathing, or sudden one-sided weakness or numbness. Get urgent care for a painful, swollen or red leg. 2 16

The labels may change soon

On June 18, 2026, HHS and the FDA asked makers to update every testosterone label. The request would:

  • Remove the line saying safety and effectiveness aren't established for "age-related" low testosterone.
  • Limit the prostate cancer ban to metastatic prostate cancer (cancer that has spread).
  • Revise the enlarged-prostate (BPH) warning. 17

As of our October 23 check, the three pill labels still carry the older wording. Kyzatrex's August 2026 label and Jatenzo's current label still list the age-related limitation and the broader prostate contraindication. 1 2 So if you read that "the FDA changed the rules," that's only half true. It asked for changes. The labels haven't caught up yet.

Our take: age alone doesn't rule you in or out. Your clinician weighs your full health picture.


Can oral testosterone affect your fertility?

Yes, testosterone in any form, including pills, can lower sperm production, and the labels say the effect on fertility may be permanent. If you want children now or in the future, see a urologist or reproductive specialist before starting. Some non-testosterone options exist, but they aren't TRT and aren't guaranteed to protect fertility. 1 2 3 8

Here's why. When testosterone comes from outside your body, your brain signals your testes to slow down. That can reduce sperm, sometimes to zero (called azoospermia). 1 2

The AUA says men with low testosterone who care about fertility should have a reproductive health evaluation before treatment. 8

This is the one section where we'll tell you plainly to slow down. A pill doesn't change this risk.

Planning on kids? Start with what to ask a reproductive specialist.

Read our guide to TRT and fertility →

If your specialist raises hCG, see questions about hCG access and cost.


How do you get a prescription for oral testosterone? Can you get it online?

You need a licensed clinician and a real diagnosis: symptoms or signs of low testosterone plus consistently low results on at least two early-morning tests. Several online services now prescribe Kyzatrex, including Hims, which launched it on October 21, 2026; your own doctor can also prescribe any of the three when appropriate. A quiz alone can't qualify you. 1 2 3 8 15 18

What counts as "confirmed" low testosterone?

Three trusted sources line up here:

  • The FDA labels: testosterone measured in the morning on at least two separate days, both below normal. 1 2 3
  • The AUA: a total testosterone below 300 ng/dL is a reasonable cutoff, measured twice, early in the morning, plus symptoms or signs. 8
  • The Endocrine Society (July 2026): at least two early-morning fasting tests, using an accurate lab test. Symptoms alone aren't enough. Clinicians should rule out fixable causes first, like obesity or certain medicines. The diagnosis works the same at any age. 15

Total testosterone is all the testosterone in your blood. Free testosterone is the small part not attached to proteins. Your clinician decides which tests you need.

One number on one day isn't a diagnosis, and 300 ng/dL is not a universal diagnostic rule. Here's how low testosterone is diagnosed.

Online service or your own doctor?

Oral testosterone products, monitoring, care routes and costs table 7: Online service or your own doctor?
Route Pills available Good for Watch out for
Online service (Henry, Hims and others) Kyzatrex Convenience and cash pay, when remote care is appropriate Age limits, state limits, membership fees
Your own doctor + maker's pharmacy program Jatenzo, Tlando, Kyzatrex Insurance users, complex health history Prior authorization, finding a willing doctor
Urology or endocrinology Any Fertility plans, age 65+, prostate history, unusual labs Wait times

18 19 20 21

Will online prescribing still be allowed after December 31, 2026?

Status as of October 23, 2026: a temporary federal rule lets DEA-registered clinicians prescribe controlled medicines like testosterone through a qualifying audio-video visit without a prior in-person evaluation through December 31, 2026, subject to the rule's conditions and applicable federal and state law. The clinician must be authorized to treat you in the state where you are located. 22

A permanent DEA "special registration" rule went to White House review in August 2026. The federal regulatory agenda lists November 2026 for final action, but that is a planned date, not a published rule. 23 State rules also apply. We'll update this section when the final rule is published.

Does insurance cover oral testosterone?

Sometimes. Your plan may require prior authorization and a trial of another formulation first. If your commercial plan covers it, maker copay cards can cut the cost. Medicare, Medicaid, TRICARE and VA prescriptions are excluded from those copay-card offers; cash programs have separate rules. 19 20

More help: testosterone prior authorization, including Medicare coverage questions


How much does oral testosterone cost?

Henry advertises Kyzatrex at $179 a month with visits, labs and medicine included, subject to its program limits. Hims lists Kyzatrex from $179 a month for medicine, with membership billed separately. Through your own doctor, Jatenzo lists conflicting $185 and $239 monthly cash prices; Tlando lists a conditional $150 offer without stating its supply length. 18 21 19 20

A price headline isn't a full quote. So we built the year-one picture for each route we could verify.

Year-one cost check (provider offers checked October 23, 2026)

Oral testosterone products, monitoring, care routes and costs table 8: Year-one cost check (provider offers checked October 23, 2026)
Route What you get Listed price 12-payment estimate Extra costs and limits
Henry — Kyzatrex FDA-approved pill Advertised $179/month, includes visits, labs, medicine, shipping $2,148 Men 35–65 only; oral TRT not available in California; quantity and lab-network limits apply
Hims — Kyzatrex FDA-approved pill From $179/month for medicine From $2,148 + membership Membership billed separately; confirm billing schedule, medicine supply and state availability
Your doctor + Tlando pharmacy program FDA-approved pill "As little as $150" Not calculable: days supplied are not stated Doctor visits, labs, possible shipping; eligibility restrictions
Your doctor + Jatenzo cash program FDA-approved pill $185 or $239 per 1-month supply (see below) $2,220 or $2,868 Doctor visits, labs; confirm which conflicting cash offer applies
Commercial insurance + copay card Jatenzo or Tlando As little as $0 Varies Prior authorization; caps apply

These estimates are our math: 12 payments at the listed monthly price. They're not quotes or proof that 365 days of medicine and every required test are covered. A complete first-year quote must include the prescribed quantity, billing dates, visits, initial and repeat testing, monitoring, shipping and any membership. 18 19 20 21

Henry's bundle has boundaries. Its program terms cap the amount of Kyzatrex supplied per 90 days; ask whether your prescribed quantity fits the advertised price. Labs arranged outside its network can cost extra. Its general terms call for cancellation at least 48 hours before renewal, and its TRT page says a remaining multi-month balance may still be due unless there is a medical reason to stop. 21 32

Hims' membership is separate. Its page shows a $49 membership charge at checkout; confirm the recurring amount and billing schedule for your plan. Its terms include two qualifying lab tests a year plus additional tests its provider finds necessary. Canceling medicine alone does not cancel membership; cancellation generally requires two days' notice, and prepaid medicine already shipped can keep membership charges running through that supply. The first membership month and shipped medicine are generally nonrefundable. 18 31

Two things we found on the makers' own pages:

  1. Jatenzo's own website lists two different cash prices. One eligibility box says $185 for a one-month supply ($150 if your commercial insurance denied coverage). Another box on the same page says $239 ($199 if denied). Until that's fixed, ask the pharmacy which price applies to you before you fill. 19
  2. Tlando's $150 offer doesn't say how many days it covers. It also says shipping may cost extra. Ask the pharmacy how many capsules and days you get for that price. 20

Want a quote you can compare? Use the questions before you pay →


Which oral testosterone claims should you double-check?

Some marketing doesn't match the FDA labels. The biggest gaps involve success rates, food rules and fertility. When a claim matters to your decision, check it against the current label on DailyMed or ask your pharmacist. 1 2 3

Oral testosterone products, monitoring, care routes and costs table 9: Which oral testosterone claims should you double-check?
Claim to check What the evidence says Our verdict
Hims reports normal levels for up to 96% of men in 90 days (launch, Oct 21, 2026) The cited trial reports 96.1% among 90-day completers and 87.8% in its more conservative analysis. The label rounds the latter to 88%. 1 18 29 Different analysis groups. The 96% figure does not mean 96% of everyone treated.
Bypasses the liver and avoids toxicity The label says these capsules are not known to cause the liver effects linked to alkylated testosterone, but tells patients to report liver symptoms. 1 Overstated. The label does not establish zero liver risk.
Take with or without food All three labels say take with food. 1 2 3 Wrong.
Oral testosterone causes less sperm suppression Labels warn it can suppress sperm and the effect may be permanent. 1 2 Not established by these labels.
"Oral TRT" for enclomiphene products Enclomiphene isn't testosterone and isn't FDA-approved. 10 11 Mislabeled.

What if a testosterone pill isn't your best fit?

A pill may not fit if you're trying to conceive soon, your blood pressure isn't controlled, the full price is beyond your budget, or a food-linked dosing routine won't stick. For cost or routine concerns, injections and FDA-approved gels are other formats to discuss. Fertility plans or uncontrolled blood pressure need clinical review before choosing any testosterone format. 1 2 3 8 14

Oral testosterone products, monitoring, care routes and costs table 10: What if a testosterone pill isn't your best fit?
If you… Better starting point Next step
Want kids now or in the future Reproductive urologist TRT and fertility
Have high or unknown blood pressure Your doctor first TRT and blood pressure
Are 65+, have prostate history or unusual labs Urology or endocrinology Low testosterone treatment options
Are considering a cream or injection Discuss FDA-approved options first; ask why a compounded product is needed if offered Male Excel research notes (below)
Want to test your levels before committing Confirm what the lab-first offer includes and when charges begin Taurus Meds research notes (below)
Have a clinician-identified need an FDA-approved option cannot meet Discuss a compounded option Hone Health research notes (below)

Disclosure: TRT Provider Guide has affiliate relationships with Male Excel, Taurus Meds and Hone Health and may earn a commission through designated paid links. Research links go directly to official research pages; the Male Excel state-availability action uses a tracked affiliate link. None of the three lists an FDA-approved swallowed testosterone capsule on the pages we checked. We list them only for readers a pill doesn't fit. See our affiliate disclosure.

Male Excel — for men fine with a cream or small daily shot

Male Excel's listed oral product, Triclozene, is not a testosterone pill. Its product page describes a compounded blend built around enclomiphene plus two ingredients marketed for thyroid support. (Its own pricing page still calls it clomiphene, so ask which you'd receive.) That isn't testosterone. If a real testosterone pill is non-negotiable, Kyzatrex through Henry or Hims is a capsule route to discuss with a clinician. 24 25

Its advertised testosterone options are small daily injections or a twice-daily cream, each paired with a thyroid tablet. Its $99 monthly membership includes unlimited e-visits with a medical provider and messaging with its support team, and it states there's no contract and you can cancel anytime. 25 Its terms say fees already charged are generally nonrefundable. 34

What it costs (provider-stated, October 2026): $99 one-time consultation and home test. Injections from $120/month or cream from $132/month (each billed every two months), plus the required $99/month membership and shipping. Twelve-paid-month examples: $2,727 for injections or $2,871 for cream, before shipping and any extra testing or medicine. That is $99 upfront plus 12 × ($120 or $132 + $99). Six advertised 60-day medicine supplies cover 360 days, so ask what it costs to cover a full 365-day year. Male Excel's site notes its compounded medicines are not FDA-approved. 24 25 34

Considering Male Excel after discussing approved and compounded options? Check whether Male Excel treats patients in your state →

Taurus Meds — for men who want to test first

Taurus Meds' oral product is enclomiphene, which helps your body make more of its own testosterone instead of replacing it. It's not testosterone and not FDA-approved. 10 26

Taurus lists $49 for labs and a physician review. Plans are listed from $149/month, including a 30-day supply and routine blood tests. 26 But its terms also list a $17.99 recurring membership fee per billing period unless the purchase terms say otherwise. Its cancellation policy describes an initial subscription charge at intake, a refund if medically disqualified, and a cancellation deadline at least 72 hours before the billing date. Confirm which charges apply to this offer before you pay. 33

Taurus's health-information privacy policy states an intent to comply with HIPAA, while its general terms say the services are not tailored to that law. Ask which policy governs your intake and medical records. 33

Want to check the testing offer and its terms first? Review Taurus Meds' stated lab-first offer →

Hone Health — a compounded troche when medically needed

Hone Health offers a testosterone troche that dissolves in your mouth. It is testosterone, but it's compounded and not FDA-approved, and the AUA prefers factory-made testosterone when possible. If you want only FDA-approved products, ask your clinician about Kyzatrex, Jatenzo or Tlando instead. Membership and medicine are billed separately. 8 27

Has your clinician identified a need an approved option cannot meet? See Hone Health's troche option and current pricing →


What should you ask before you pay?

A good oral TRT quote names the exact medicine, the care included and what you're agreeing to. Bring these questions to any clinic, doctor or pharmacist before you start. The answers protect your health and your wallet.

Copy or print this table and record the answers before you pay.

Oral testosterone products, monitoring, care routes and costs table 11: What should you ask before you pay?
Ask this Why it matters Your answer
What exact medicine is this? Kyzatrex, Jatenzo, Tlando, or compounded? "Oral TRT" can mean five different things.
Was my low testosterone confirmed from symptoms or signs and two early-morning tests? It's required by the labels and guidelines.
Should I see a specialist first because of fertility plans? Testosterone can lower sperm count, possibly for good.
When and at what time is my first monitoring blood test? Each pill uses a different clock.
How often will you check my blood pressure and hematocrit? Both are listed warnings.
Which pharmacy will fill my prescription, how many days does one fill cover, and when is a refill arranged? Prices often hide the supply length; refill timing affects continuity.
What's my full year-one cost: medicine, membership, initial screening, any repeat diagnostic test, monitoring labs, visits and shipping? Teaser prices aren't totals; "labs included" does not explain every testing stage.
What happens if I cancel or need to switch brands? Some plans bill the rest of a prepaid term; brands aren't swappable.
Who handles side effects or abnormal results, and how do I reach them? Customer support and clinical care are different.
How can I obtain my lab results and treatment records for another clinician, including after cancellation? You need a clear way to continue care.

1 2 3 8 18 21

Still sorting out which route makes sense? Use TRT Provider Guide's Find My TRT Path tool as an educational starting point →


How did we research this page?

We read the current FDA labels for the oral testosterone products discussed here, the AUA guideline, the Endocrine Society's 2026 statement, the federal telemedicine rule and the June 2026 FDA label request. We checked each provider's public pricing page and recorded the date. We separate label facts, provider claims and our own judgment.

  • Label facts come from DailyMed and FDA approval records.
  • Provider claims (prices, inclusions, cancellation) come from each company's own pages on October 23, 2026. We did not buy, enroll or test.
  • Our judgments (who each route fits) are based only on those verified facts.
  • What would change our conclusions: a head-to-head trial, updated labels after the June 2026 request, price changes, or the DEA's final telemedicine rule.

Full details: How We Review TRT Providers. Read our editorial standards or report a possible error.


Oral testosterone FAQ: What else should you know?

These pills require a prescription, food-linked dosing and follow-up testing. Switching, travel, alcohol and stopping treatment each raise questions to resolve with your clinician or pharmacist.

Is oral testosterone better than injections?

Not better, different. Pills avoid testosterone injections and gel transfer but usually need two doses a day with food; Kyzatrex has a once-daily exception. Injection schedules and costs depend on the product and care plan. These label studies do not establish that the pills work as well as injections. 1 2 3

How often do you take oral testosterone?

Usually twice a day, morning and evening, with food. Kyzatrex's lowest prescribed regimen is once a day in the morning. Your clinician sets your dose. 1 2 3

Is there a generic oral testosterone?

An authorized generic of Kyzatrex, called Undecatrex, is listed on DailyMed under Kyzatrex's FDA application. A listing doesn't mean your pharmacy stocks it or that it's cheaper, so ask. 28

Can you buy testosterone pills over the counter?

No. Testosterone is a Schedule III controlled substance and needs a prescription. Over-the-counter "boosters" are not approved testosterone treatment. 1 12

Can women take oral testosterone?

Kyzatrex, Jatenzo and Tlando are not approved for women and must not be used during pregnancy. Women with testosterone questions should talk with a women's health clinician. 1 2

Can I switch from injections to a pill?

Possibly, with your clinician. Expect a new prescription and new monitoring. Don't swap brands on your own; the labels say they aren't interchangeable. 1 3

Is oral testosterone okay if I'm over 65?

Maybe. Older-adult evidence is limited: Jatenzo's main study included no men over 65, while Kyzatrex's label contains conflicting age information. Henry states an upper age limit of 65. Your clinician weighs blood pressure, prostate and heart risk. 1 2 21

Can I drink alcohol on oral testosterone?

In a Kyzatrex study, alcohol taken with a high-fat meal didn't change how the drug was absorbed. That's not a safety green light. Ask your clinician. 1

What happens if I stop taking it?

Talk with your clinician before stopping. Symptoms can return if the cause of your low testosterone remains. Plan follow-up testing and symptom review with your clinician. 8 Here's what to expect when you stop TRT.

Can I travel with testosterone pills?

Travel may be possible with a valid prescription, but check your destination and every layover's medicine rules. Keep it in the original labeled container and confirm storage and refill plans; a U.S. prescription does not guarantee permission to bring it into another country. 30 How to travel with testosterone.


This page is educational information, not medical advice. Call 911 for chest pain, trouble breathing, or sudden one-sided weakness or numbness. Get urgent care for a swollen, painful or red leg.

Still exploring online TRT programs? Use our free Find My TRT Path tool as an educational starting point.


Sources

  1. KYZATREX prescribing information — DailyMed (revised August 2026; checked October 23, 2026)
  2. JATENZO prescribing information — DailyMed (revised September 2025; DailyMed updated October 13, 2026)
  3. TLANDO prescribing information — DailyMed (checked October 2026)
  4. FDA approval package — Kyzatrex, NDA 213953
  5. FDA approval package — Jatenzo, NDA 206089
  6. FDA approval letter — Tlando, NDA 208088
  7. METHITEST (methyltestosterone) label — DailyMed · FDA approval record, ANDA 080767
  8. AUA: Evaluation and Management of Testosterone Deficiency · Published AUA guideline, accessible copy
  9. FDA: Compounding and the FDA — Questions and Answers
  10. Operation Supplement Safety: Clomiphene and enclomiphene are drugs, not supplements
  11. Clomiphene citrate label — DailyMed
  12. FDA: Caution—Bodybuilding Products Can Be Risky
  13. Swerdloff & Dudley (2020): A new oral testosterone undecanoate therapy comes of age for the treatment of hypogonadal men
  14. ANDROGEL prescribing information — DailyMed (secondary exposure warning)
  15. Endocrine Society: Statement on Testosterone Replacement Therapy (July 16, 2026)
  16. American Heart Association: Heart attack and stroke symptoms
  17. HHS: Requested updates to testosterone therapy labels (June 18, 2026)
  18. Hims: Expanded testosterone care with injectable and oral TRT (October 21, 2026) · Hims testosterone page
  19. JATENZO: Help paying for Jatenzo (both eligibility boxes checked October 23, 2026)
  20. TLANDO: Preferred Pharmacy Network program · TLANDO copay card
  21. Henry Meds: Testosterone therapy
  22. Federal Register: Fourth temporary extension of telemedicine flexibilities
  23. OIRA: Special Registrations for Telemedicine and Limited State Telemedicine Registrations, pending review · Federal regulatory agenda, planned final action
  24. Male Excel: Triclozene
  25. Male Excel: Hormone treatment costs
  26. Taurus Meds: Enclomiphene
  27. Hone Health: Plus membership and treatments
  28. UNDECATREX label — DailyMed (authorized generic under NDA 213953)
  29. Bernstein & Dhingra (2024): A phase III, single-arm, 6-month trial of a wide-dose range oral testosterone undecanoate product
  30. CDC: Traveling Abroad with Medicine
  31. Hims & Hers: Terms and Conditions, TRT Membership Terms (updated October 20, 2026)
  32. Henry Meds: Program terms · Terms of Service
  33. Taurus Meds: Terms of Service, membership fees · Cancellation and Refund Policy · Health Care Information Privacy Policy
  34. Male Excel: TRT FAQ · Terms and Conditions

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